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Merck
CN

15480

Sigma-Aldrich

Boc-Phe-OH

≥99.0% (T)

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别名:
N-(叔丁氧羰基)-L-苯基丙氨酸, Boc-L-苯丙氨酸
线性分子式:
C6H5CH2CH(COOH)NHCOOC(CH3)3
CAS号:
分子量:
265.30
Beilstein:
2219729
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

≥99.0% (T)

形式

solid

旋光性

[α]20/D +25±1°, c = 1% in ethanol

反应适用性

reaction type: Boc solid-phase peptide synthesis
reaction type: C-H Activation
reagent type: ligand
reaction type: Peptide Synthesis

mp

85-87 °C (lit.)

应用

peptide synthesis

官能团

amine
carboxylic acid

SMILES字符串

CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(O)=O

InChI

1S/C14H19NO4/c1-14(2,3)19-13(18)15-11(12(16)17)9-10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/m0/s1

InChI key

ZYJPUMXJBDHSIF-NSHDSACASA-N

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WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Yong Chen et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 99, 103-113 (2015-12-22)
The objective was to investigate the topical iontophoretic delivery of a series of amino acid ester prodrugs of aciclovir (ACV-X, where ACV=aciclovir and X=Arg, Gly, Ile, Phe, Trp and Val) as a means to enhance cutaneous delivery of ACV. The
Matthew J Crawford et al.
Journal of nucleic acids, 2011, 652702-652702 (2011-07-22)
Conformationally preorganized peptide nucleic acids (PNAs) have been synthesized through backbone modifications at the γ-position, where R = alanine, valine, isoleucine, and phenylalanine side chains. The effects of these side-chains on the conformations and hybridization properties of PNAs were determined
Jie Chen et al.
Archives of pharmacal research, 37(1), 142-148 (2013-11-23)
Novel thermo- and pH-dual responsive amphiphilic copolymers were synthesized based on hyperbranched polyethylenimine (PEI) by grafting L-phenylalanine. The phenylalanine-modified PEI exhibited lower cytotoxicity than commercial PEI. These copolymers showed the phenomena of phase transitions in response to pH and temperature.
Yan Yan et al.
Drug design, development and therapy, 13, 681-694 (2019-03-13)
Budesonide (Bud) is a nonhalogenated glucocorticoid with high anti-inflammatory potency and low systemic side effects. However, the poor water solubility of Bud affects its dissolution and release behavior, thus influencing its anti-inflammatory effect. This study was aimed at synthesizing and
Yasuhiro Tsume et al.
Molecular pharmaceutics, 5(5), 717-727 (2008-07-26)
Dipeptide monoester prodrugs of floxuridine were synthesized, and their chemical stability in buffers, resistance to glycosidic bond metabolism, affinity for PEPT1, enzymatic activation and permeability in cancer cells were determined and compared to those of mono amino acid monoester floxuridine

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