product name
N-(叔-叔丁氧羰基)-L-丙氨酸, ≥99.0% (TLC)
质量水平
检测方案
≥99.0% (TLC)
旋光性
[α]20/D −25±1°, c = 2% in acetic acid
反应适用性
reaction type: Boc solid-phase peptide synthesis
reaction type: C-H Activation
reagent type: ligand
reaction type: Peptide Synthesis
mp
79-83 °C (lit.)
应用
peptide synthesis
官能团
amine
carboxylic acid
SMILES字符串
C[C@H](NC(=O)OC(C)(C)C)C(O)=O
InChI
1S/C8H15NO4/c1-5(6(10)11)9-7(12)13-8(2,3)4/h5H,1-4H3,(H,9,12)(H,10,11)/t5-/m0/s1
InChI key
QVHJQCGUWFKTSE-YFKPBYRVSA-N
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相关类别
应用
Boc-Ala-OH可用于:
- 制备N-炔丙基丙氨酸,其是生成N-(3-芳基)丙基丙氨酸残基的关键前体。
- 解析3,3′-双(苄氧基)-1,1′-双萘-2,2′-二醇的外消旋混合物。
- 通过一锅法合成同时包含酰胺和酰亚胺官能团的混合三肽模拟物。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Synthesis of N-(3-arylpropyl) amino acid derivatives by sonogashira types of reaction in aqueous media
Organic Letters, 3(18), 2823-2826 (2001)
Convenient synthesis and efficient resolution of 3, 3′-bis (benzyloxy)-1, 1′-binaphthalene-2, 2′-diol
Tetrahedron Asymmetry, 14(10), 1393-1396 (2003)
A facile one pot route for the synthesis of imide tethered peptidomimetics
Organic & Biomolecular Chemistry, 14(2), 556-563 (2016)
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(1), 192-207 (2020-01-10)
The peptide sequence KKIRVRLSA was synthesized in a dimeric structure (SET-M33DIM) and evaluated as a candidate drug for infections due to multidrug-resistant (MDR) Gram-negative pathogens. SET-M33DIM showed significant antibacterial activity against MDR strains of Klebsiella pneumoniae, Acinetobacter baumannii, and Escherichia
Analytica chimica acta, 865, 53-59 (2015-03-04)
Polydimethylsiloxane (PDMS) is widely used for microfabrication and bioanalysis; however, its surface functionalization is limited due to the lack of active functional groups and incompatibility with many solvents. We presented a novel approach for in situ fabrication of cleavable peptide
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