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质量水平
方案
≥98.0% (NT)
反应适用性
reagent type: cross-linking reagent
折射率
n20/D 1.458 (lit.)
n20/D 1.458
沸点
72-80 °C/0.1 mmHg (lit.)
密度
1.012 g/mL at 20 °C (lit.)
官能团
Boc
amine
SMILES字符串
NCCNC(OC(C)(C)C)=O
InChI
1S/C7H16N2O2/c1-7(2,3)11-6(10)9-5-4-8/h4-5,8H2,1-3H3,(H,9,10)
InChI key
AOCSUUGBCMTKJH-UHFFFAOYSA-N
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应用
- Facile synthesis of new N-(aminocycloalkylene) amino acid compounds:描述N-Boc-乙二胺在2-{[2-(Boc-氨基)乙基]氨基}乙酸苄酯制备中的应用(G Matulevičiūtė et al., 2023)。
- Synthesis of a new tripod BODIPY dye:报道N-Boc-乙二胺参与化学合成BODIPY染料(H Wang et al., 2022)。
- Single‐Entity Electrocatalysis:讨论N-Boc-乙二胺在电催化用改性Co3O4纳米颗粒中的应用(T Quast et al., 2021)。
其他说明
乙二胺的单保护衍生物,制备药理活性类似物;引入乙二胺间隔基。
警示用语:
Danger
危险声明
危险分类
Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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The Journal of organic chemistry, 68(4), 1630-1632 (2003-02-15)
An improved synthesis of ethyl N-[(2-Boc-amino)ethyl]glycinate and its hydrochloride salt is reported. The synthesis is based on the reductive alkylation of Boc-ethylenediamine with ethyl glyoxylate hydrate and furnishes the title compound in near quantitative yield and high purity without chromatography.
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Basic nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups were prepared and evaluated as novel hypoxic cell selective cytotoxic agents. In vitro, N-(2-aminoethyl)-N-methyl-3-nitro-4-(1-methyl-1-nitroethyl)benzene sulfonamide hydrochloride (11) proved to be preferentially toxic to hypoxic EMT6 mammary carcinoma cells. At 1 mM concentration in
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A new molecule 4 [(GGH-DAE)2DHQ] associating the 1,4,5,8-tetrahydroxyanthraquinone ring (DHQ) of the antitumor drug mitoxantrone (2), two diaminoethylene chains (DAE), and the metal-chelating peptide Gly-Gly-His (GGH) has been synthesized. Such a molecule presents characteristics able to induce antitumor activity: compound
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Analytical biochemistry, 205(2), 369-371 (1992-09-01)
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