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线性分子式:
(CH3)3COCONHCH2CH2NH2
化学文摘社编号:
分子量:
160.21
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1932330
产品名称
N-Boc-乙二胺, ≥98.0% (NT)
InChI
1S/C7H16N2O2/c1-7(2,3)11-6(10)9-5-4-8/h4-5,8H2,1-3H3,(H,9,10)
SMILES string
NCCNC(OC(C)(C)C)=O
InChI key
AOCSUUGBCMTKJH-UHFFFAOYSA-N
assay
≥98.0% (NT)
reaction suitability
reagent type: cross-linking reagent
refractive index
n20/D 1.458 (lit.)
n20/D 1.458
bp
72-80 °C/0.1 mmHg (lit.)
density
1.012 g/mL at 20 °C (lit.)
functional group
Boc
amine
Quality Level
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Application
- Facile synthesis of new N-(aminocycloalkylene) amino acid compounds:描述N-Boc-乙二胺在2-{[2-(Boc-氨基)乙基]氨基}乙酸苄酯制备中的应用(G Matulevičiūtė et al., 2023)。
- Synthesis of a new tripod BODIPY dye:报道N-Boc-乙二胺参与化学合成BODIPY染料(H Wang et al., 2022)。
- Single‐Entity Electrocatalysis:讨论N-Boc-乙二胺在电催化用改性Co3O4纳米颗粒中的应用(T Quast et al., 2021)。
Other Notes
乙二胺的单保护衍生物,制备药理活性类似物;引入乙二胺间隔基。
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Small (Weinheim an der Bergstrasse, Germany), 14(30), e1703115-e1703115 (2018-07-03)
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Russell D Viirre et al.
The Journal of organic chemistry, 68(4), 1630-1632 (2003-02-15)
An improved synthesis of ethyl N-[(2-Boc-amino)ethyl]glycinate and its hydrochloride salt is reported. The synthesis is based on the reductive alkylation of Boc-ethylenediamine with ethyl glyoxylate hydrate and furnishes the title compound in near quantitative yield and high purity without chromatography.
W S Saari et al.
Journal of medicinal chemistry, 34(10), 3132-3138 (1991-10-01)
Basic nitrobenzenesulfonamides containing nitroisopropyl and (ureidooxy)methyl groups were prepared and evaluated as novel hypoxic cell selective cytotoxic agents. In vitro, N-(2-aminoethyl)-N-methyl-3-nitro-4-(1-methyl-1-nitroethyl)benzene sulfonamide hydrochloride (11) proved to be preferentially toxic to hypoxic EMT6 mammary carcinoma cells. At 1 mM concentration in
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Journal of medicinal chemistry, 36(15), 2084-2090 (1993-07-23)
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