所有图片(2)
别名:
3-氨基-4-氰基吡唑
经验公式（希尔记法）:
C4H4N4
CAS号:
分子量:
108.10
Beilstein:
2647
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
推荐产品
质量水平
检测方案
97%
mp
172-174 °C (lit.)
SMILES字符串
Nc1n[nH]cc1C#N
InChI
1S/C4H4N4/c5-1-3-2-7-8-4(3)6/h2H,(H3,6,7,8)
InChI key
FFNKBQRKZRMYCL-UHFFFAOYSA-N
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应用
3-amino-4-cyanopyrazole was used to study the impurities in zaleplon bulk drug.
Building block used in the synthesis of a variety of heterocycles.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
WGK
WGK 3
个人防护装备
Eyeshields, Gloves, type N95 (US)
Ch Bharathi et al.
Journal of pharmaceutical and biomedical analysis, 44(1), 101-109 (2007-03-21)
Zaleplon is a pyrazolopyrimidine derivative and possesses sedative and hypnotic properties. Seven unknown impurities in zaleplon bulk drug at levels below 0.1% were detected by reverse-phase high performance liquid chromatography (HPLC). The starting material, 3-amino-4-cyanopyrazole and an intermediate, N-[3-[3-(dimethylamino)-1-oxo-2-propenyl]-phenyl]-N-ethylacetamide (DOPEA)
Synlett, 65-65 (2006)
Helvetica Chimica Acta, 89, 30-30 (2006)
Alessandro Antonelli et al.
Molecular and cellular endocrinology, 393(1-2), 56-64 (2014-06-17)
CLM29 (a pyrazolo[3,4-d]pyrimidine, that inhibits RET, epidermal growth factor receptor, vascular endothelial growth factor receptor, and has an anti-angiogenic activity) has anti-neoplastic activity in papillary dedifferentiated thyroid cancer. Here we tested CLM29 in medullary thyroid cancer (MTC), in primary MTC
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