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Merck
CN

15304

6-(Boc-氨基)-1-己醇

≥98.0% (GC)

别名:

N-(6-羟基己基)氨基甲酸叔丁酯

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关于此项目

线性分子式:
(CH3)3CO2CNH(CH2)6OH
化学文摘社编号:
分子量:
217.31
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3604498
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产品名称

6-(Boc-氨基)-1-己醇, ≥98.0% (GC)

InChI

1S/C11H23NO3/c1-11(2,3)15-10(14)12-8-6-4-5-7-9-13/h13H,4-9H2,1-3H3,(H,12,14)

SMILES string

OCCCCCCNC(OC(C)(C)C)=O

InChI key

BDLPJHZUTLGFON-UHFFFAOYSA-N

assay

≥98.0% (GC)

reaction suitability

reagent type: cross-linking reagent

functional group

Boc
amine
hydroxyl

Quality Level

Other Notes

连接基;制备碘化物

Application

6-(Boc-amino)-1-hexanol can be used as a reactant to synthesize:
  • Hsp90 fluorescent probes applicable in the development of an FP assay for the Hsp90 chaperone.
  • 1-Guanidino-7-aminoheptane (GC7) analogs as potent deoxyhypusine synthase inhibitors.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J.K. Dutton et al.
Journal of the Chemical Society. Perkin Transactions 1, 2581-2581 (1995)
Synthesis of novel fluorescent probes for the molecular chaperone Hsp90
Llauger-Bufi L, et al.
Bioorganic & Medicinal Chemistry Letters, 13(22), 3975-3978 (2003)
Novel hydroxylamine-containing analogues of 1-guanidino-7-aminoheptane (GC7), an effective inhibitor of deoxyhypusine synthase.
Khomutov MA, et al.
Russian Journal of Bioorganic Chemistry, 42(4), 415-422 (2016)
Małgorzata Maksymowicz et al.
Cell communication and signaling : CCS, 18(1), 176-176 (2020-11-06)
Lymphotoxin β receptor (LTβR) is a member of tumor necrosis factor receptor (TNFR) superfamily which regulates the immune response. At the cellular level, upon ligand binding, the receptor activates the pro-inflammatory NF-κB and AP-1 pathways. Yet, the intracellular distribution of

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