152633
橄榄醇
95%
别名:
1,3-二羟基-5-戊苯, 3,5-二羟基戊基苯, 5-戊基间苯二酚
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关于此项目
线性分子式:
CH3(CH2)4C6H3-1,3-(OH)2
化学文摘社编号:
分子量:
180.24
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
207-908-8
MDL number:
Assay:
95%
Form:
solid
InChI key
IRMPFYJSHJGOPE-UHFFFAOYSA-N
InChI
1S/C11H16O2/c1-2-3-4-5-9-6-10(12)8-11(13)7-9/h6-8,12-13H,2-5H2,1H3
SMILES string
CCCCCc1cc(O)cc(O)c1
assay
95%
form
solid
mp
46-48 °C (lit.)
Quality Level
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Application
橄榄油醇在分子印迹聚合物 (MIP) 的合成中被用作模板分子 。它也用作重组 CYP2C19 的（S） -苯丙氨酸4'-羟化酶活性的抑制剂 。
signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 1 Oral - STOT SE 2 Oral
target_organs
Central nervous system,Blood, Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
M G Cascio et al.
British journal of pharmacology, 149(4), 431-440 (2006-09-06)
We have previously reported the development of CB-25 and CB-52, two ligands of CB1 and CB2 cannabinoid receptors. We assessed here their functional activity. The effect of the two compounds on forskolin-induced cAMP formation in intact cells or GTP-gamma-S binding
M Fellermeier et al.
FEBS letters, 427(2), 283-285 (1998-06-02)
A new enzyme, geranylpyrophosphate:olivetolate geranyltransferase (GOT), the first enzyme in the biosynthesis of cannabinoids could be detected in extracts of young leaves of Cannabis sativa. The enzyme accepts geranylpyrophosphate (GPP) and to a lesser degree also nerylpyrophosphate (NPP) as a
Lewis J Kearsey et al.
The FEBS journal, 287(8), 1511-1524 (2019-10-13)
In the native pathway to therapeutic cannabinoid biosynthesis in Cannabis sativa, the three-step production of a key intermediate, olivetolic acid, is catalysed by the enzymes tetraketide synthase (TKS; linear tetraketide intermediate production in two stages) and olivetolic acid cyclase (OAC; final
Rongrong Jiang et al.
Drug metabolism and pharmacokinetics, 28(4), 332-338 (2013-01-16)
The present study investigated the inhibitory effect of cannabidiol (CBD), a major constituent of marijuana, on the catalytic activity of cytochrome P450 2C19 (CYP2C19). (S)-Mephenytoin 4'-hydroxylase activities of human liver microsomes (HLMs) and recombinant CYP2C19 were inhibited by CBD in
R H McClanahan et al.
Journal of natural products, 47(5), 828-834 (1984-09-01)
A study of the biotransformation of olivetol by Syncephalastrum racemosum ATCC 18192 has led to the isolation of three metabolites, which were identified as 4'-hydroxy-olivetol, 3-(3,5-dihydroxyphenyl)-1-propanol, and 3-(3,5-dihydroxyphenyl)-1-propanoic acid. The structures of the isolated metabolites were deduced by comparison of
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