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Merck
CN

15035

(Boc-氨氧基)乙酸

≥98.0% (T)

别名:

N-Boc-(羧基甲氧基)胺

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关于此项目

线性分子式:
(CH3)3CO2CNHOCH2CO2H
化学文摘社编号:
分子量:
191.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6137646
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产品名称

(Boc-氨氧基)乙酸, ≥98.0% (T)

InChI

1S/C7H13NO5/c1-7(2,3)13-6(11)8-12-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)

SMILES string

CC(C)(C)OC(=O)NOCC(O)=O

InChI key

QBXODCKYUZNZCY-UHFFFAOYSA-N

assay

≥98.0% (T)

form

powder

mp

~115 °C (dec.)

functional group

amine
carboxylic acid

Quality Level

Other Notes

用于向多肽引入羟胺部分;与醛反应可生成肟。

Application

(Boc-氨氧基)乙酸可用于制备Boc-氨氧基四(乙二醇)

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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O. Nyanguile et al.
Lett. Pept. Sci., 1, 9-9 (1994)
J. Shao et al.
Journal of the American Chemical Society, 117, 3893-3893 (1995)
Site-specific protein immobilization through N-terminal oxime linkages.
Journal of Materials Chemistry, 17(19), 2021-2027 (2007)
Mariarosaria De Simone et al.
Contrast media & molecular imaging, 11(6), 561-571 (2017-01-05)
Superparamagnetic iron oxide nanoparticles (SPIONs) have received increasing interest as contrast media in biomedical imaging and innovative therapeutic tools, in particular for loco-regional ablative treatments and drug delivery. The future of therapeutic applications would strongly benefit from improving the capability
Rory K Morgan et al.
ACS chemical biology, 10(8), 1778-1784 (2015-05-16)
ADP-ribosylation is essential for cell function, yet there is a dearth of methods for detecting this post-translational modification in cells. Here, we describe a clickable aminooxy alkyne (AO-alkyne) probe that can detect cellular ADP-ribosylation on acidic amino acids following Cu-catalyzed

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