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Merck
CN

149837

Sigma-Aldrich

2-乙氧基-1-乙氧羰基-1,2-二氢喹啉

≥99%, for peptide synthesis

别名:

2-乙氧基-1,2-二氢-1-喹啉羧酸乙酯, N-乙氧羰基-2-乙氧基-1,2-二氢喹啉, EEDQ

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About This Item

经验公式(希尔记法):
C14H17NO3
CAS号:
分子量:
247.29
Beilstein:
533048
EC 号:
MDL编号:
UNSPSC代码:
12352005
PubChem化学物质编号:
NACRES:
NA.22

产品名称

2-乙氧基-1-乙氧羰基-1,2-二氢喹啉, ≥99%

质量水平

方案

≥99%

表单

solid

反应适用性

reaction type: Coupling Reactions

mp

62-67 °C (lit.)

应用

peptide synthesis

官能团

ether

储存温度

2-8°C

SMILES字符串

CCOC1C=Cc2ccccc2N1C(=O)OCC

InChI

1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3

InChI key

GKQLYSROISKDLL-UHFFFAOYSA-N

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一般描述

2-乙氧基-1-乙氧羰基-1,2-二氢喹啉(EEDQ)是稳定试剂,可用于高产率制备酰胺和多肽。本品提供现成货品。室温下,可溶于含有机溶剂的水性介质,但不溶于水。 用作肽合成偶联剂。

应用

2-乙氧基-1-乙氧羰基-1,2-二氢喹啉用作偶联剂:
  • 用于壳聚糖及其两亲性衍生物的区域选择性季铵化。
  • 用于制备酰胺型S-MA(扁桃酸)衍生物修饰的石英晶体微天平(QCM)传感器。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

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Chunmei You et al.
Scientific reports, 10(1), 8400-8400 (2020-05-23)
Two unique housefly strains, PSS and N-PRS (near-isogenic line with the PSS), were used to clarify the mechanisms associated with propoxur resistance in the housefly, Musca domestica. The propoxur-selected resistant (N-PRS) strain exhibited >1035-fold resistance to propoxur and 1.70-, 12.06-
L Carbonell et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 14(6), 497-502 (2004-12-14)
One of the most effective psychotherapeutic agents in the treatment of bipolar disease is lithium. Chronic lithium treatment affects some signal transduction mechanisms such as cAMP, cGMP, inositol 1,4,5 P(3), Gi protein, protein kinase C and can also modify gene
Analía Bortolozzi et al.
The international journal of neuropsychopharmacology, 13(10), 1299-1314 (2010-02-18)
Atypical antipsychotic drugs (APDs) increase dopamine (DA) release in prefrontal cortex (PFC), an effect probably mediated by the direct or indirect activation of the 5-HT(1A) receptor (5-HT(1A)R). Given the very low in-vitro affinity of most APDs for 5-HT(1A)Rs and the
Eur. J. Pharmacol., Molec. Pharmacol. Sec., 269, 25-25 (1994)

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