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Merck
CN

149233

2,6-二甲基-2,5-庚二烯-4-酮

95%

别名:

佛尔酮, 对称-二异亚丙基丙酮

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线性分子式:
(CH3)2C=CHCOCH=C(CH3)2
化学文摘社编号:
分子量:
138.21
EC Number:
207-986-3
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1699751
MDL number:
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InChI key

MTZWHHIREPJPTG-UHFFFAOYSA-N

InChI

1S/C9H14O/c1-7(2)5-9(10)6-8(3)4/h5-6H,1-4H3

SMILES string

C\C(C)=C\C(=O)\C=C(\C)C

vapor density

4.8 (vs air)

vapor pressure

0.38 mmHg ( 20 °C), 1 mmHg ( 42 °C)

assay

95%

refractive index

n20/D 1.497 (lit.)

bp

198-199 °C (lit.)

mp

23-26 °C (lit.)

density

0.885 g/mL at 25 °C (lit.)

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

174.2 °F - closed cup

flash_point_c

79 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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M Spanò et al.
Mutation research, 397(1), 37-43 (1998-02-17)
Diepoxybutane is one of the key metabolites of butadiene, a compound of high environmental and occupational concern. The effects of diepoxybutane on mouse reproductive cells have been previously characterized by flow cytometry demonstrating a specific, dose-dependent cytotoxicity for differentiating spermatogonia.
T Oguro et al.
The Journal of pharmacology and experimental therapeutics, 287(2), 773-778 (1998-11-10)
Phorone, a glutathione (GSH) depletor, induces the expression of mRNAs of heme oxygenase-1 (HO-1) and c-jun by mediating the activation of activated protein-1 (AP-1) in rat livers. We have shown that phorone activates c-Jun N-terminal kinase (JNK), thus leading to
G Mehmetçik et al.
Research communications in molecular pathology and pharmacology, 96(3), 353-356 (1997-06-01)
The levels of lipid peroxidation product (malondialdehyde = MDA) and vitamin C and the activities of glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) were determined in the liver and its mitochondrial fraction, in the rats 2 and 18 hr after
Hidenari Nagai et al.
Hepatology (Baltimore, Md.), 36(1), 55-64 (2002-06-27)
The effect of reduced glutathione (GSH) depletion by acetaminophen (APAP), diethylmaleate (DEM), or phorone on the mode of cell death and susceptibility to tumor necrosis factor (TNF)-induced cell death was studied in cultured mouse hepatocytes. Dose-dependent necrosis was the exclusive
V Gogvadze et al.
Redox report : communications in free radical research, 5(6), 359-363 (2001-01-05)
The seleno-organic compound ebselen mimics the glutathione-dependent, hydroperoxide reducing activity of glutathione peroxidase. The activity of glutathione peroxidase determines the rate of hydroperoxide-induced Ca2+ release from mitochondria. Ebselen stimulates Ca2+ release from mitochondria, accelerates mitochondrial respiration and uncoupling, and induces

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