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产品名称
3-羟基邻氨基苯甲酸, 97%
质量水平
方案
97%
表单
solid
反应适用性
reaction type: solution phase peptide synthesis
mp
240 °C (dec.) (lit.)
应用
peptide synthesis
SMILES字符串
Nc1c(O)cccc1C(O)=O
InChI
1S/C7H7NO3/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3,9H,8H2,(H,10,11)
InChI key
WJXSWCUQABXPFS-UHFFFAOYSA-N
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此商品 | 65390 | 246557 | 184802 |
|---|---|---|---|
| assay 90% | assay 99% (AT) | assay 99% | assay 95% |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| form solid | form solid | form powder | form solid |
一般描述
3-羟基邻氨基苯甲酸是一种氨基苯甲酸，通常用作各种化学反应的中间体。[1]
应用
<ul>
<li><strong>直接抑制酶以减轻喹啉酸的形成：</strong>用于在色氨酸分解代谢的犬尿氨酸途径中合成 2-氨基-3-羧基粘康酸半醛 (ACMS)（Sanz 等人，2022 年）。</li>
</ul>
<li><strong>直接抑制酶以减轻喹啉酸的形成：</strong>用于在色氨酸分解代谢的犬尿氨酸途径中合成 2-氨基-3-羧基粘康酸半醛 (ACMS)（Sanz 等人，2022 年）。</li>
</ul>
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Guifang Gan et al.
Cell death discovery, 7(1), 173-173 (2021-07-08)
Sorafenib is the FDA-approved first-line target drug for HCC patients. However, sorafenib only confers 3-5 months of survival benefit with <30% of HCC patients. Thus, it is necessary to develop a sensitizer for hepatocellular carcinoma (HCC) to sorafenib. Here, we
NO scavenging by 3-hydroxyanthranilic acid and 3-hydroxykynurenine: N-nitrosation leads via oxadiazoles to o-quinone diazides
C Backhaus, et al.
Nitric Oxide, 19, 237-244 (2008)
Andrea Moglia et al.
Metabolic engineering, 12(3), 223-232 (2009-11-28)
Phenolic esters like chlorogenic acid play an important role in therapeutic properties of many plant extracts. We aimed to produce phenolic esters in baker's yeast, by expressing tobacco 4CL and globe artichoke HCT. Indeed yeast produced phenolic esters. However, the
E R Werner et al.
Biological chemistry Hoppe-Seyler, 366(1), 99-102 (1985-01-01)
3-Hydroxyanthranilic acid was identified in lymphocyte cultures during allogeneic stimulation. The metabolite and the synthetic product have identical HPLC retention times, fluorescence spectra, fluorescence intensities as a function of pH value and electrochemical behaviour.
F A Teulings et al.
Acta vitaminologica et enzymologica, 29(1-6), 108-112 (1975-01-01)
In comparison with healthy age- and sex-comparable subjects, a significantly higher concentration of unconjugated 3-hydroxyanthranilic acid was detected in the urine of untreated bladder and kidney carcinoma patients. Because of tryptophan metabolite 3-hydroxyanthranilic acid is suspected to be involved in
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