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Merck
CN

146358

Sigma-Aldrich

N-乙基-2-吡咯烷酮

98%

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别名:
NEP
经验公式(希尔记法):
C6H11NO
CAS号:
分子量:
113.16
Beilstein:
107971
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

形式

liquid

折射率

n20/D 1.465 (lit.)

bp

97 °C/20 mmHg (lit.)

密度

0.992 g/mL at 25 °C (lit.)

SMILES字符串

CCN1CCCC1=O

InChI

1S/C6H11NO/c1-2-7-5-3-4-6(7)8/h2-5H2,1H3

InChI key

ZFPGARUNNKGOBB-UHFFFAOYSA-N

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一般描述

1-乙基-2-吡咯烷酮是一种透皮吸收增强化合物,其对角质层脂质的多层脂质体的作用机制已被研究

应用

1-乙基-2-吡咯烷酮用于通过光固化而修饰椰壳纤维(来源于椰子( Cocos nucifera))

象形图

Health hazardCorrosion

警示用语:

Danger

危险声明

危险分类

Eye Dam. 1 - Repr. 1B

WGK

WGK 1

闪点(°F)

195.8 °F

闪点(°C)

91 °C

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Effect of Pretreatment with Ultraviolet Radiation on the Physicomechanical Properties of Photocured Coir (Cocos nucifera) Fiber with 1-Ethyl-2-Pyrrolidone (1-E-2-P) Monomer.
Khan MA, et al.
Polymer-Plastics Technology and Engineering, 45(4), 487-494 (2006)
Effect of penetration enhancers (pyrrolidone derivatives) on multilamellar liposomes of stratum corneum lipid: a study by UV spectroscopy and differential scanning calorimetry.
Kim C-K, et al.
International Journal of Pharmaceutics, 95(1), 43-50 (1993)
Takeshi Katsuda et al.
Scientific reports, 3, 1197-1197 (2013-02-05)
Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ) in the brain because of an imbalance between Aβ production and clearance. Neprilysin (NEP) is the most important Aβ-degrading enzyme in the brain. Thus, researchers have explored virus-mediated
Ajeet Kaushik et al.
Scientific reports, 7, 45663-45663 (2017-04-05)
In this research, we demonstrate cell uptake of magneto-electric nanoparticles (MENPs) through nanoelectroporation (NEP) using alternating current (ac)-magnetic field stimulation. Uptake of MENPs was confirmed using focused-ion-beam assisted transmission electron microscopy (FIB-TEM) and validated by a numerical simulation model. The
Małgorzata Sobocińska et al.
Amino acids, 51(8), 1201-1207 (2019-07-16)
Rat sialorphin (Gln-His-Asn-Pro-Arg) is a natural blocker of neprilysin (NEP) that belongs to the family of endogenous opioid peptide-degrading enzymes. Studies have confirmed the efficiency of sialorphin in blocking the activity of NEP, both in vitro and in vivo. It

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