146358
N-乙基-2-吡咯烷酮
98%
别名:
NEP
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关于此项目
经验公式（希尔记法）:
C6H11NO
化学文摘社编号:
分子量:
113.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-250-6
Beilstein/REAXYS Number:
107971
MDL number:
产品名称
N-乙基-2-吡咯烷酮, 98%
InChI key
ZFPGARUNNKGOBB-UHFFFAOYSA-N
InChI
1S/C6H11NO/c1-2-7-5-3-4-6(7)8/h2-5H2,1H3
SMILES string
CCN1CCCC1=O
assay
98%
form
liquid
refractive index
n20/D 1.465 (lit.)
bp
97 °C/20 mmHg (lit.)
density
0.992 g/mL at 25 °C (lit.)
Quality Level
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Application
1-乙基-2-吡咯烷酮用于通过光固化而修饰椰壳纤维（来源于椰子（ Cocos nucifera））。
General description
1-乙基-2-吡咯烷酮是一种透皮吸收增强化合物，其对角质层脂质的多层脂质体的作用机制已被研究。
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
195.8 °F - Pensky-Martens closed cup
flash_point_c
91 °C - Pensky-Martens closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Ajeet Kaushik et al.
Scientific reports, 7, 45663-45663 (2017-04-05)
In this research, we demonstrate cell uptake of magneto-electric nanoparticles (MENPs) through nanoelectroporation (NEP) using alternating current (ac)-magnetic field stimulation. Uptake of MENPs was confirmed using focused-ion-beam assisted transmission electron microscopy (FIB-TEM) and validated by a numerical simulation model. The
Takeshi Katsuda et al.
Scientific reports, 3, 1197-1197 (2013-02-05)
Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ) in the brain because of an imbalance between Aβ production and clearance. Neprilysin (NEP) is the most important Aβ-degrading enzyme in the brain. Thus, researchers have explored virus-mediated
Effect of penetration enhancers (pyrrolidone derivatives) on multilamellar liposomes of stratum corneum lipid: a study by UV spectroscopy and differential scanning calorimetry.
Kim C-K, et al.
International Journal of Pharmaceutics, 95(1), 43-50 (1993)
Effect of Pretreatment with Ultraviolet Radiation on the Physicomechanical Properties of Photocured Coir (Cocos nucifera) Fiber with 1-Ethyl-2-Pyrrolidone (1-E-2-P) Monomer.
Khan MA, et al.
Polymer-Plastics Technology and Engineering, 45(4), 487-494 (2006)
Małgorzata Sobocińska et al.
Amino acids, 51(8), 1201-1207 (2019-07-16)
Rat sialorphin (Gln-His-Asn-Pro-Arg) is a natural blocker of neprilysin (NEP) that belongs to the family of endogenous opioid peptide-degrading enzymes. Studies have confirmed the efficiency of sialorphin in blocking the activity of NEP, both in vitro and in vivo. It
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