推荐产品
质量水平
方案
98%
表单
powder
mp
60-63 °C (lit.)
官能团
chloro
ester
thioether
储存温度
2-8°C
SMILES字符串
CCOC(=O)c1cnc(SC)nc1Cl
InChI
1S/C8H9ClN2O2S/c1-3-13-7(12)5-4-10-8(14-2)11-6(5)9/h4H,3H2,1-2H3
InChI key
SNNHLSHDDGJVDM-UHFFFAOYSA-N
应用
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate was used in the synthesis of pyrimidinopyridones, potential inhibitors of the FMS tyrosine kinase.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Hui Huang et al.
Bioorganic & medicinal chemistry letters, 18(7), 2355-2361 (2008-03-18)
A series of pyrimidinopyridones has been designed, synthesized and shown to be potent and selective inhibitors of the FMS tyrosine kinase. Introduction of an amide substituent at the 6-position of the pyridone core resulted in a significant potency increase. Compound
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