所有图片(1)
别名:
NSC 117338
经验公式（希尔记法）:
C9H7NO3
CAS号:
分子量:
177.16
Beilstein:
153214
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
推荐产品
质量水平
检测方案
≥96.5%
形式
powder
mp
249 °C (dec.) (lit.)
溶解性
chloroform/ethanol (1:1): soluble 50 mg/mL, clear to slightly hazy, yellow to brown
SMILES字符串
Oc1ccc2[nH]c(cc2c1)C(O)=O
InChI
1S/C9H7NO3/c11-6-1-2-7-5(3-6)4-8(10-7)9(12)13/h1-4,10-11H,(H,12,13)
InChI key
BIMHWDJKNOMNLD-UHFFFAOYSA-N
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一般描述
用KMnO 4氧化5-羟基吲哚-2-羧酸，生成吡咯-2,3,5-三羧酸。
应用
5-羟吲哚-2-羧酸用于血浆、血小板和尿液中血清素的HPLC-安培检测。
- 吲哚 C5-O-取代开环-环丙基吲哚类化合物的合成及其抗癌活性
- 微波组合合成 5-HT1A、5-HT2A 和 5-HT2C 受体配体吲哚芳基哌嗪衍生物的反应物
- 制备新型天然辐射防护剂黑色素的反应物
- 5-羟吲哚-2-羧酸酰胺类组胺-3 受体反向激动剂的合成
- 用于制备构象约束的信号转导和转录激活因子 3 (Stat3) 的类肽抑制剂的反应物
- 用于制备恶二唑类似物的反应物，作为酪氨酸激酶 ZAP-70 的非肽类 SH2 抑制剂
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
S Ito et al.
The Biochemical journal, 143(1), 207-217 (1974-10-01)
The reflecting material of the tapetum lucidum of the sea catfish (Arius felis) was chromatographed on Sephadex LH-20 in methanol-dimethyl sulphoxide-formic acid. Two components were present: one, showing an absorption maximum at 330nm, was tapetal pigment; the other, at 257nm
E Pussard et al.
Clinical chemistry, 42(7), 1086-1091 (1996-07-01)
We describe an isocratic liquid-chromatographic method with amperometric detection for determination of serotonin by rapid sample preparation. Platelet-poor plasma and platelets were injected after a single deproteinization step with perchloric acid. Addition of sodium borohydride to whole blood avoids oxidation
Zebin Lin et al.
Biomedical chromatography : BMC, 33(10), e4626-e4626 (2019-06-22)
N-Ethylpentylone (NEP) is a popular synthetic cathinone abused worldwide. To obtain more information about its pharmacokinetics and pharmacodynamics, a rapid, simple and sensitive liquid chromatography-tandem mass spectrometry method was developed for the determination of NEP, two important neurotransmitters, dopamine and
Yifeng Zeng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1110-1111, 133-143 (2019-02-27)
Gut microbiota-host co-metabolites play an essential role in maintaining homeostasis, and their concentration changes are closely related to a variety of diseases. Developing a targeted metabolomics analytical platform for these co-metabolites will help to elucidate the relationship between intestinal flora
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