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Merck
CN

143219

Sigma-Aldrich

4-溴苯肼 盐酸盐

99%

别名:

1-(4-Bromophenyl)hydrazine hydrochloride, 2-(4-Bromophenyl)hydrazinium chloride, 4-Bromophenylhydrazine monohydrochloride, p-Bromophenylhydrazine monohydrochloride

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About This Item

线性分子式:
BrC6H4NHNH2·HCl
CAS号:
分子量:
223.50
Beilstein:
3565838
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

99%

形式

powder

mp

220-230 °C (dec.) (lit.)

SMILES字符串

Cl.NNc1ccc(Br)cc1

InChI

1S/C6H7BrN2.ClH/c7-5-1-3-6(9-8)4-2-5;/h1-4,9H,8H2;1H

InChI key

RGGOWBBBHWTTRE-UHFFFAOYSA-N

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应用

4-Bromophenylhydrazine hydrochloride was used as reagent in the synthesis of:
  • acylsulfonamides and acylsulfamides
  • 9-bromo-2-ethenyl-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one

象形图

Corrosion

警示用语:

Danger

危险声明

危险分类

Skin Corr. 1B

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Xu Xie et al.
European journal of medicinal chemistry, 40(7), 655-661 (2005-06-07)
The introduction of side chains bearing epoxide motifs into the molecular scaffold of kenpaullone and 9-trifluoromethylpaullone led to improved antiproliferative activity of the novel derivatives for human tumor cell lines. The syntheses were accomplished applying Stille coupling for the introduction
Michael P Winters et al.
Bioorganic & medicinal chemistry letters, 18(6), 1926-1930 (2008-03-01)
A series of novel acylsulfonamide, acylsulfamide, and sulfonylurea bioisosteres of carboxylic acids were prepared as CXCR2 antagonists. Structure-activity relationships are reported for these series. One potent orally bioavailable inhibitor had excellent PK properties and was active in a lung injury
Siva Doddi et al.
Journal of fluorescence, 26(6), 1939-1949 (2016-11-01)
We report the synthesis and characterization of a new fluorescent dyad SP-DPP-SP(9) via efficient palladium-catalyzed Sonogashira coupling of prop-2-yn-1-yl 3-(3',3'dimethyl-6-nitrospiro[chromene-2,2'-indolin]-1'-yl)propanoatespiropyran, SP(8), a well known photochromic accepter, with 3,6-bis(5-bromothiophen-2-yl)-2,5-bis((R)-2-ethylhexyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione, DPP(4), a highly fluorescent donor. Under visible light exposure the SP unit
Ilkoo Noh et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 5(3), 1700481-1700481 (2018-03-30)
A noninvasive and selective therapy, photodynamic therapy (PDT) is widely researched in clinical fields; however, the lower efficiency of PDT can induce unexpected side effects. Mitochondria are extensively researched as target sites to maximize PDT effects because they play crucial

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