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143073

Sigma-Aldrich

二甘醇酸

98%

别名:

2,2′-氧二乙酸

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About This Item

线性分子式:
O(CH2COOH)2
CAS号:
110-99-6
分子量:
134.09
Beilstein:
1072117
EC 号:
203-823-5
MDL编号:
MFCD00004309
UNSPSC代码:
12352100
PubChem化学物质编号:
24848573
NACRES:
NA.22

质量水平

200

方案

98%

mp

140-144 °C (lit.)

溶解性

ethanol: soluble 5%, clear to slightly hazy, colorless to greenish-yellow

官能团

carboxylic acid
ether

SMILES字符串

OC(=O)COCC(O)=O

InChI

1S/C4H6O5/c5-3(6)1-9-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

QEVGZEDELICMKH-UHFFFAOYSA-N

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相关类别

一般描述

二乙醇酸是一种二甘醇 (DEG) 的有毒代谢产物，可引起DEG诱导的近端肾小管坏死。

应用

二乙醇酸已被用于从硝酸钙水溶液中制备针状文石颗粒。

生化/生理作用

二乙醇酸具有抗血栓形成特性，并可诱导血管舒张。它可抑制人近端小管细胞中的琥珀酸脱氢酶活性。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

预防措施声明

P301 + P312 + P330

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
MKCW1943
MKCW3352
MKCV5211
MKCV5212
MKCW9684

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Diethylene glycol (DEG) is a solvent used in consumer products allowing the increased risk for consumer exposure. DEG metabolism produces two primary metabolites, 2-hydroxyethoxyacetic acid (2-HEAA) and diglycolic acid (DGA). DGA has been shown to be the toxic metabolite responsible
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Carboxymethyl starches are added to food products for thickening or tablet binding/filling purposes. Although they lack toxicity, their synthesis creates the chemical byproduct diglycolic acid (DGA), which is difficult to eliminate and whose toxicity is in question. A rare case
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