质量水平
检测方案
98%
形式
powder
bp
262 °C (lit.)
mp
239-241 °C (lit.)
溶解性
pyridine: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
SMILES字符串
O=C(Nc1ccccc1)Nc2ccccc2
InChI
1S/C13H12N2O/c16-13(14-11-7-3-1-4-8-11)15-12-9-5-2-6-10-12/h1-10H,(H2,14,15,16)
InChI key
GWEHVDNNLFDJLR-UHFFFAOYSA-N
基因信息
human ... EPHX2(2053)
mouse ... Ephx2(13850)
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一般描述
1,3-二苯基脲是一种存在于水果和蔬菜中的细胞分裂素化合物 。
生化/生理作用
1,3-二苯基脲由从内盖夫荒漠污染的短生沙漠河床分离的温和嗜盐菌海杆菌属代谢。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Sebastian R Sørensen et al.
FEMS microbiology letters, 213(2), 199-204 (2002-08-09)
A moderate halophilic Marinobacter sp. (designated strain DPUZ) able to metabolize 1,3-diphenylurea (DPU) was isolated from a contaminated ephemeral desert stream bed near an industrial complex in the northern part of the Negev Desert (Israel). Metabolism of DPU was accompanied
N Campillo et al.
Talanta, 116, 376-381 (2013-10-24)
The paper presents a novel approach for the determination of three cytokinin compounds, thidiazuron (TDZ), 1,3-diphenylurea (1,3-DPU) and forchlorfenuron (CPPU), in fruit and vegetables samples using liquid chromatography with electrospray ionization and time-of-flight mass spectrometry (LC-ESI-TOFMS). Analytes were extracted from
Joshua R Brown et al.
Bioorganic & medicinal chemistry, 19(18), 5585-5595 (2011-08-16)
The treatment of tuberculosis is becoming more difficult due to the ever increasing prevalence of drug resistance. Thus, it is imperative that novel anti-tuberculosis agents, with unique mechanisms of action, be discovered and developed. The direct anti-tubercular testing of a
Nadezhda German et al.
European journal of medicinal chemistry, 43(11), 2453-2463 (2008-03-25)
Bacterial efflux pump systems contribute to antimicrobial resistance in pathogenic bacteria. The co-administration of bacterial efflux pump inhibitors with antibiotics is being pursued to overcome efflux-mediated resistance to antibiotics. In this study we investigated a strategy for converting broad-spectrum efflux
Paul Bamborough et al.
Journal of medicinal chemistry, 54(14), 5131-5143 (2011-06-28)
A kinase-focused screening set of fragments has been assembled and has proved successful for the discovery of ligand-efficient hits against many targets. Here we present some of our general conclusions from this exercise. Notably, we present the first profiling results
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