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质量水平
方案
97%
表单
powder
mp
157-159 °C (lit.)
官能团
iodo
SMILES字符串
Oc1c(I)cc(I)cc1I
InChI
1S/C6H3I3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H
InChI key
VAPDZNUFNKUROY-UHFFFAOYSA-N
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此商品 | 142387 | 19566 | 36543 |
|---|---|---|---|
| Quality Level 100 | Quality Level 200 | Quality Level - | Quality Level - |
| mp 157-159 °C (lit.) | mp −43 °C (lit.) | mp 157-159 °C (lit.) | mp 64-66 °C (lit.) |
| form powder | form liquid | form - | form - |
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Cristina Rueda et al.
Antimicrobial agents and chemotherapy, 52(3), 1150-1152 (2007-12-28)
The anticryptosporidial activity of Bobel-24 (2,4,6-triiodophenol) was studied for the first time, resulting in a reduction of the in vitro growth of Cryptosporidium of up to 99.6%. In a SCID mouse model of chronic cryptosporidiosis, significant differences (P < 0.05)
Matilde Parreño et al.
Cancer research, 68(15), 6313-6323 (2008-08-05)
The poor prognosis of pancreatic cancer and poor sensitivity to current therapeutics, associated with resistance to apoptosis, urge the search for new drugs. We previously described the induction of caspase-independent mithochondrial death in leukemia cells by Bobel-24 (AM-24) and derivatives.
Iñaki F Trocóniz et al.
Pharmaceutical research, 23(7), 1533-1542 (2006-06-20)
The aim of this study was to explore the possibility of achieving a practical dosing regimen for 2,4,6-triiodophenol (AM-24), a new leukotriene B4 (LTB4) synthesis inhibitor. First, a model capable of dealing with the nonlinearity in its pharmacokinetic profile was
José Antonio Castro-Hermida et al.
Veterinary parasitology, 155(3-4), 308-313 (2008-06-27)
The efficacy of the anti-inflammatory drug Bobel-24 against experimental infection by Cryptosporidium parvum was evaluated in neonatal lambs. The animals were treated by oral administration of the drug at 50 or 500 mg/kg of body weight. The prophylactic/therapeutic treatment was
Matilde Parreño et al.
Molecular cancer therapeutics, 5(5), 1166-1175 (2006-05-30)
2,4,6-Triiodophenol (Bobel-24, AM-24) was originally described as a nonsteroid antiinflammatory molecule. We have synthesized three derivatives of Bobel-24 (Bobel-4, Bobel-16, and Bobel-30) and tested their activities as putative antileukemic agents. We have found that Bobel-24 and Bobel-16 were dual inhibitors
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