推荐产品
质量水平
方案
97%
表单
liquid
折射率
n20/D 1.588 (lit.)
沸点
109-110 °C/12 mmHg (lit.)
密度
1.565 g/mL at 25 °C (lit.)
官能团
bromo
chloro
SMILES字符串
Clc1cccc(CBr)c1
InChI
1S/C7H6BrCl/c8-5-6-2-1-3-7(9)4-6/h1-4H,5H2
InChI key
LZIYAIRGDHSVED-UHFFFAOYSA-N
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一般描述
3-Chlorobenzyl bromide reacts with aminoethanol and NaH to yield aminoethyl 3-chlorobenzyl ether.
应用
3-Chlorobenzyl bromide was used in the synthesis of symmetrical and unsymmetrical benzyl thioethers. It was used as starting reagent during the synthesis of 1-(3-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole dihydrochloride.
警示用语：
Danger
危险声明
危险分类
Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
Convenient and robust one-pot synthesis of symmetrical and unsymmetrical benzyl thioethers from benzyl halides using thiourea.
Eccles KS, et al.
ARKIVOC (Gainesville, FL, United States), ix, 216-218 (2010)
Selective inactivation of monoamine oxidase B by aminoethyl 3-chlorobenzyl ether.
Ding CZ and Silverman RB.
Bioorganic & Medicinal Chemistry, 3(10), 2077-2078 (1993)
Jason Z Vlahakis et al.
Bioorganic & medicinal chemistry, 21(21), 6788-6795 (2013-09-12)
Several analogs based on the lead structure of 1-(4-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole (clemizole) were synthesized and evaluated as novel inhibitors of heme oxygenase (HO). Many of the compounds were found to be potent and highly selective for the HO-2 isozyme (constitutive), and had
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