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Merck
CN

135933

Sigma-Aldrich

5-氯-2-羟基吡啶

97%

别名:

5-氯-2-吡啶醇

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About This Item

经验公式(希尔记法):
C5H4ClNO
CAS号:
分子量:
129.54
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:

检测方案

97%

mp

163-165 °C (lit.)

SMILES字符串

Oc1ccc(Cl)cn1

InChI

1S/C5H4ClNO/c6-4-1-2-5(8)7-3-4/h1-3H,(H,7,8)

InChI key

SZFUWUOHDRMCKD-UHFFFAOYSA-N

一般描述

5-氯-2-羟基吡啶作为供体配体,以两性离子形式存在,即 5-氯吡啶-2-酸酯存在于铜配合物中

应用

用 5-氯-2-羟基吡啶 (5-chloro-2-pyridinol) 研究双香豆素对黄嘌呤脱氢酶的影响 及黄嘌呤脱氢酶还原丝裂霉素 C 的机理

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Ji-Xin Yuan et al.
Acta crystallographica. Section C, Crystal structure communications, 58(Pt 4), M270-M272 (2002-04-05)
In the title compound, [Cu(C(5)H(4)ClNO)(2)(C(4)H(4)N(2))(H(2)O)(2)](ClO(4))(2), the Cu atom, which lies on an inversion centre, has an octahedral environment. The pyrazine ligand also lies about an inversion centre and links adjacent Cu atoms into a chain running along the b axis;
D L Gustafson et al.
Cancer research, 52(24), 6936-6939 (1992-12-15)
These studies examined the effect of dicumarol on xanthine dehydrogenase (XDH), an enzyme recently shown to bioreduce mitomycin C. Dicumarol, which has previously been shown to inhibit xanthine oxidase (XO), inhibited both XDH and XO mediated conversion of xanthine to
D L Gustafson et al.
Cancer research, 53(22), 5470-5474 (1993-11-15)
These studies examined the kinetic and mechanistic parameters of mitomycin C (MMC) bioreduction by xanthine dehydrogenase (XDH), an enzyme recently shown to be capable of MMC activation. The bioreduction of MMC by XDH leads to the formation of 2,7-diaminomitosene (2,7-DM)

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