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蒸汽密度
~3 (vs air)
质量水平
蒸汽压
~13 mmHg ( 20 °C)
方案
≥96%
自燃温度
802 °F
折射率
n20/D 1.394 (lit.)
沸点
120 °C (lit.)
mp
−93 °C (lit.)
溶解性
H2O: slightly soluble
organic solvents: miscible
密度
0.992 g/mL at 25 °C (lit.)
官能团
amine
nitro
SMILES字符串
CC(C)[N+]([O-])=O
InChI
1S/C3H7NO2/c1-3(2)4(5)6/h3H,1-2H3
InChI key
FGLBSLMDCBOPQK-UHFFFAOYSA-N
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一般描述
人 SULT1A1 可将 2-硝基丙烷转化为致突变代谢产物。
应用
以 5，5-二甲基吡咯啉氮氧化物和 5，5-二（三氘甲基）吡咯啉氮氧化物为原料，合成了 5，5-二甲基吡咯啉氮氧化物和 5，5-二（三氘甲基）吡咯啉氮氧化物 。也用于确定一对结构异构体（2-硝基丙烷 (2-NP) 和 1-硝基丙烷 (1-NP)）的结果一致性 。
警示用语：
Danger
危险分类
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 1B - Flam. Liq. 3 - Muta. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 3
闪点(°F)
78.8 °F - closed cup
闪点(°C)
26 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
Yuko Doi et al.
Journal of toxicologic pathology, 24(4), 207-213 (2012-02-10)
This study was conducted to determine the concordance of results for a pair of structural isomers, 2-nitropropane (2-NP) and 1-nitropropane (1-NP), using the rat medium-term liver carcinogenesis bioassay (Ito test) and previously published long-term carcinogenicity tests. Male F344 rats were
Ethel A Wilhelm et al.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 61(3), 197-203 (2008-09-27)
This study was undertaken to investigate if the introduction of trifluoromethyl (F(3)C) group into diphenyl diselenide (PhSe)(2) molecule causes acute toxicity in rats. It was further examined if the presence of F(3)C group in (PhSe)(2) molecule alters the protective effect
Lysandro P Borges et al.
Chemico-biological interactions, 160(2), 99-107 (2006-02-01)
The effect of post-treatment with diphenyl diselenide on liver damage induced by 2-nitropropane (2-NP) was examined in male rats. Rats were pre-treated with a single dose of 2-NP (100 mg/kg body weight dissolved in canola oil). Afterward, the animals were
Kirk Simon et al.
Mechanisms of ageing and development, 130(9), 637-647 (2009-08-15)
The p53 DNA damage response attenuated with age and we have evaluated downstream factors in the DNA damage response. In old animals p21 protein accumulates in the whole cell fraction but significantly declines in the nucleus, which may alter cell
Diane C Cabelof et al.
The journals of gerontology. Series A, Biological sciences and medical sciences, 61(5), 427-434 (2006-05-25)
Young (4- to 6-month-old) and aged (24- to 28-month-old) mice were exposed to 2-nitropropane (2-NP), a DNA oxidizing agent, and the ability to induce DNA polymerase beta (beta-pol) and AP endonuclease (APE) was determined. In contrast to the inducibility of
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