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Merck
CN

129585

Sigma-Aldrich

马来酰亚胺

99%

别名:

2,5-吡咯二酮

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About This Item

经验公式(希尔记法):
C4H3NO2
CAS号:
分子量:
97.07
Beilstein:
106910
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

99%

表单

powder

mp

91-93 °C (lit.)

官能团

maleimide

SMILES字符串

O=C1NC(=O)C=C1

InChI

1S/C4H3NO2/c6-3-1-2-4(7)5-3/h1-2H,(H,5,6,7)

InChI key

PEEHTFAAVSWFBL-UHFFFAOYSA-N

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一般描述

马来酰亚胺(2,5-吡咯二酮)是一种新型纳米颗粒表面官能团,易于与细胞穿透肽偶联。通过点击化学可以实现偶联,从而保留其生物功能。

马来酰亚胺可用作Diels Alder反应的亲二烯体(dienophile),用于合成大分子。

应用

铑催化的芳基硼酸共轭芳基化反应。
马来酰亚胺官能化二氧化硅颗粒可用于固定牛血清白蛋白(BSA)-硼酸(BA)偶联物

象形图

Skull and crossbonesCorrosion

警示用语:

Danger

危险声明

危险分类

Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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The furan/maleimide Diels--Alder reaction: A versatile click--unclick tool in macromolecular synthesis
Gandini A.
Progress in Polymer Science, 38, 1-29 (2013)
Tetrahedron Letters, 48, 4413-4413 (2007)
Meng Ke et al.
PLoS computational biology, 13(6), e1005603-e1005603 (2017-06-16)
GLUT1 facilitates the down-gradient translocation of D-glucose across cell membrane in mammals. XylE, an Escherichia coli homolog of GLUT1, utilizes proton gradient as an energy source to drive uphill D-xylose transport. Previous studies of XylE and GLUT1 suggest that the
Paulo L Onuchic et al.
Scientific reports, 9(1), 12161-12161 (2019-08-23)
Liquid-liquid phase separation (LLPS) of RNA-protein complexes plays a major role in the cellular function of membraneless organelles (MLOs). MLOs are sensitive to changes in cellular conditions, such as fluctuations in cytoplasmic ion concentrations. To investigate the effect of these
Satya Nandana Narla et al.
Biochemical and biophysical research communications, 443(2), 562-567 (2013-12-12)
We report bovine serum albumin (BSA)-boronic acid (BA) conjugates as lectin mimetics and their glyco-capturing capacity. The BSA-BA conjugates were synthesized by amidation of carboxylic acid groups in BSA with aminophenyl boronic acid in the presence of EDC, and were

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