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Merck
CN

129453

Sigma-Aldrich

3-吲哚乙腈

98%

别名:

3-(氰甲基)吲哚, IAN, NSC 523272, 吲哚-3-乙腈, 吲哚乙腈

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About This Item

经验公式(希尔记法):
C10H8N2
CAS号:
分子量:
156.18
Beilstein:
125488
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

表单

solid

沸点

157-160 °C/0.2 mmHg (lit.)

mp

33-36 °C (lit.)

官能团

nitrile

SMILES字符串

N#CCc1c[nH]c2ccccc12

InChI

1S/C10H8N2/c11-6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5H2

InChI key

DMCPFOBLJMLSNX-UHFFFAOYSA-N

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一般描述

3-吲哚乙腈 (indolylacitrithione) 是一种光诱导的生长素抑制物质,从轻质甘蓝 ( Brassica olearea L.) 枝条中分离得到 。它抑制 大肠杆菌 O157:H7 和 铜绿假单胞菌 的生物膜形成,而不影响其生长

应用

反应物用于制备:
  • 色氨酸双加氧酶抑制剂吡啶基-乙烯基-吲哚作为潜在的抗癌免疫调节剂
  • 组蛋白脱乙酰酶抑制剂
  • 潜在激酶抑制剂
  • Kv7/KCNQ 钾通道激活剂
  • 驱动蛋白特异性 MKLP-2 抑制剂
  • 杀虫剂
  • 潜在 PET 癌症显像剂
  • 作为动脉粥样硬化治疗的法尼酯 X 受体 (FXR) 激动剂
  • 丁酰胆碱酯酶抑制剂
  • 坏死性凋亡抑制剂

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

233.6 °F - closed cup

闪点(°C)

112 °C - closed cup

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Light-induced auxin-inhibiting substance from cabbage (Brassica oleacea L.) shoots.
Kosemura S, et al.
Tetrahedron Letters, 38(48), 8327-8330 (1997)
Ewa Ciska et al.
Journal of agricultural and food chemistry, 57(6), 2334-2338 (2009-03-19)
The aim of the study was to investigate the effect of the boiling process on the content of ascorbigen, indole-3-carbinol, indole-3-acetonitrile, and 3,3'-diindolylmethane in fermented cabbage. The cabbage was boiled for 5 to 60 min. Boiling resulted in a decrease
Xuejin Zhao et al.
Viruses, 13(8) (2021-08-29)
Influenza A viruses are serious zoonotic pathogens that continuously cause pandemics in several animal hosts, including birds, pigs, and humans. Indole derivatives containing an indole core framework have been extensively studied and developed to prevent and/or treat viral infection. This
Yukako Komaki et al.
Journal of environmental sciences (China), 58, 231-238 (2017-08-05)
Disinfection by-products occur widely as the unintended effect of water disinfection and are associated with toxicity and adverse human health effects. Yet the molecular mechanisms of their toxicity are not well understood. To investigate the molecular basis of hyperploidy induction
Pedro Robles et al.
Plant physiology, 152(3), 1357-1372 (2010-01-02)
To identify genes involved in vascular patterning in Arabidopsis (Arabidopsis thaliana), we screened for abnormal venation patterns in a large collection of leaf shape mutants isolated in our laboratory. The rotunda1-1 (ron1-1) mutant, initially isolated because of its rounded leaves

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