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Merck
CN

128635

Sigma-Aldrich

2-羟基乙基甲基丙烯酸酯

contains ≤250 ppm monomethyl ether hydroquinone as inhibitor, 97%

别名:

HEMA, 乙二醇单甲基丙烯酸酯, 甲基丙烯酸2-羟乙酯

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About This Item

线性分子式:
CH2=C(CH3)COOCH2CH2OH
CAS号:
分子量:
130.14
Beilstein:
1071583
EC 号:
MDL编号:
UNSPSC代码:
12162002
PubChem化学物质编号:
NACRES:
NA.23

蒸汽密度

5 (vs air)

质量水平

蒸汽压

0.01 mmHg ( 25 °C)

方案

97%

表单

liquid

包含

≤250 ppm monomethyl ether hydroquinone as inhibitor

折射率

n20/D 1.453 (lit.)

沸点

67 °C/3.5 mmHg (lit.)

密度

1.073 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

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一般描述

甲基丙烯酸羟乙酯(HEMA)是第一个被用于合成生物医学用水凝胶的单体。通过与更多的亲水单体聚合,可增强HEMA的吸水膨胀性。HEMA在药物发现中被广泛应用。

应用

HEMA被用于合成生物功能性聚(甲基丙烯酸羟乙酯)(PHEMA)共聚物。它还被用于制备用于药物递送的PHEMA光响应膜、 基于HEMA/丙烯酰胺的特殊药物释放水凝胶 以及水溶性HEMA/甲基丙烯酸水凝胶。可研究HEMA对牙髓干细胞迁移(体外)的影响。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

222.8 °F - closed cup

闪点(°C)

106 °C - closed cup


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Giovanna C R M Schver et al.
International journal of pharmaceutics, 581, 119292-119292 (2020-04-04)
The use of water-insoluble carriers for amorphous solid dispersions (ASDs) has attracted more recent interest as the kinetic solubility profiles (KSP) from these systems can achieve a more sustained level of supersaturation when compared with ASDs based on water-soluble polymers.
Drake W Williams et al.
Journal of endodontics, 39(9), 1156-1160 (2013-08-21)
Cell migration is an important step in pulpal wound healing. Although components in the resin-based dental materials are known to have adverse effects on pulp wound healing including proliferation and mineralization, their effects on cell migration have been scarcely examined.
Influence of the ionic character of a drug on its release rate from hydrogels based on 2-hydroxyethylmethacrylate and acrylamide synthesized by photopolymerization
Gomez ML, et al.
Express Polymer Letters, 6(30, 189-197 (2012)
Thomas J Dursch et al.
Biomaterials, 35(2), 620-629 (2013-10-24)
Two-photon confocal microscopy and back extraction with UV/Vis-absorption spectrophotometry quantify equilibrium partition coefficients, k, for six prototypical drugs in five soft-contact-lens-material hydrogels over a range of water contents from 40 to 92%. Partition coefficients were obtained for acetazolamide, caffeine, hydrocortisone
Preparation of Light-responsive Membranes by a Combined Surface Grafting and Postmodification Process.
Scholler K, et al.
Journal of Visualized Experiments, 85, e51680-e51680 (2014)

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