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文件

126268

2,4-二羟基嘧啶-5-羧酸

Name: 2,4-二羟基嘧啶-5-羧酸
Brand: ALDRICH

95%

别名:

异乳清酸, 脲嘧啶-5-羧酸

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About This Item

经验公式（希尔记法）:

C₅H₄N₂O₄

CAS号:

23945-44-0

分子量:

156.10

EC 号:

245-947-2

MDL编号:

MFCD00006023

UNSPSC代码:

12352100

PubChem化学物质编号:

24847711

NACRES:

NA.22

质量水平

100

检测方案

95%

形式

powder

mp

283 °C (dec.) (lit.)

SMILES字符串

OC(=O)C1=CNC(=O)NC1=O

InChI

1S/C5H4N2O4/c8-3-2(4(9)10)1-6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)

InChI key

ZXYAAVBXHKCJJB-UHFFFAOYSA-N

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一般描述

2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. It has been used to synthesize N1-alkylated uracil derivatives.

应用

2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been used for the visual sensing of melamine (at parts-per-billion (ppb) level) by a highly sensitive analytical method based on Au nanoparticles.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Naked eye sensing of melamine using rationally tailored gold nanoparticles: hydrogen-bonding and charge-transfer recognition.

Raj Kumar Bera et al.

The Analyst, 136(8), 1644-1648 (2011-02-25)

A highly sensitive analytical method based on Au nanoparticles rationally tailored with recognition elements uracil-5-carboxylic acid (UCA) and 2,4,6-trinitrobenzenesulfonic acid (TNBS) for the visual sensing of melamine at the parts-per-billion (ppb) level is described. The tailored Au nanoparticles function as

Metabolism of pyrimidine deoxyribonucleosides in Neurospora crassa.

P M Shaffer et al.

Journal of bacteriology, 121(2), 648-655 (1975-02-01)

The experiments in this report involve the following series of reactions which were previously demonstrated with purified enzyme preparations from Neurospora crassa: thymidine a yields thymine ribonucleoside b yields thymine c yields 5-hydroxymethyluracil d yields 5-formyluracil e yields uracil-5-carboxylic acid

New uracil dimers showing erythroid differentiation inducing activities.

Alessandro Accetta et al.

Journal of medicinal chemistry, 52(1), 87-94 (2008-12-17)

The synthesis of C5 linked uracil dimers was carried out according to a model developed in order to bind adenine in DNA. N1-Alkylated uracil derivatives were synthesized from isoorotic acid (uracil-5-carboxylic acid) or thymine. The carboxylic acid derivatives were condensed

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