推荐产品
检测方案
97%
mp
87-90 °C (lit.)
SMILES字符串
Nc1ccc(Cl)c(N)c1
InChI
1S/C6H7ClN2/c7-5-2-1-4(8)3-6(5)9/h1-3H,8-9H2
InChI key
ZWUBBMDHSZDNTA-UHFFFAOYSA-N
一般描述
4-Chloro-1,3-diaminobenzene is dye precursor useful in manufacture of hair dyes.
应用
4-Chloro-1,3-diaminobenzene has been used to study the mutagenic effect of phenylenediamines hair chemicals on Salmonella typhimurium TA 102.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Charity Mosley-Foreman et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 46(12), 3780-3784 (2008-10-23)
Phenylenediamines (PD) are dye precursors used to manufacture hair dyes. The three PDs, 1,2-,1,3-, and 1,4-PD and three chlorinated PDs, 4-chloro-1,2-PD, 4-chloro-1,3-PD, and 4,5-dichloro-1,2-PD were studied for their mutagenic effect in Salmonella typhimurium TA 102, cytotoxicity in human skin keratinocyte
E K Weisburger et al.
Carcinogenesis, 1(6), 495-499 (1980-06-01)
In both male and female Fischer rats, feeding 4-chloro-o-phenylenediamine at 0.5 or 1% in the diet led to a significant increase in hyperplasia, papilloma and carcinoma of the urinary bladder. Neoplastic nodules of the liver and squamous cell papillomas of
4-Chloro-ortho-phenylenediamine and 4-chloro-meta-phenylenediamine.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 27, 81-89 (1982-04-01)
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