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Merck
CN

124087

Sigma-Aldrich

2-溴-4-甲基苯胺

98%

别名:

2-溴-对甲苯胺, 4-氨基-3-溴甲苯

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About This Item

线性分子式:
BrC6H3(CH3)NH2
CAS号:
分子量:
186.05
Beilstein:
1931711
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

98%

表单

liquid

折射率

n20/D 1.602 (lit.)

沸点

240 °C (lit.)

mp

14-16 °C (lit.)

密度

1.5 g/mL at 25 °C (lit.)

官能团

bromo

SMILES字符串

Cc1ccc(N)c(Br)c1

InChI

1S/C7H8BrN/c1-5-2-3-7(9)6(8)4-5/h2-4H,9H2,1H3

InChI key

UVRRJILIXQAAFK-UHFFFAOYSA-N

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一般描述

2-Bromo-4-methylaniline participates in palladium catalyzed selective amination of 3-bromoquinoline to yield 3-(2-bromo-4-methylphenylamino) quinoline. It reacts with ethyl and methyl imidazo[1,2-a]pyridine-2-carboxylates in the presence of Me3Al to form amide.

应用

2-Bromo-4-methylaniline has been used in the synthesis of iminophosphoranes.

象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

230.0 °F - closed cup

闪点(°C)

110 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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Synthesis and reactivity of ortho-palladated arylcarbodiimides and aryl isothiocyanates. Formation of C-palladated quinazolines. Synthesis of 2-aminoquinolines.
Vicente J, et al.
Organometallics, 23(20), 4711-4722 (2004)
Synthesis of 7H-indolo [2, 3-c] quinolines: study of the Pd-catalyzed intramolecular arylation of 3-(2-bromophenylamino) quinolines under microwave irradiation.
Hostyn S, et al.
Tetrahedron, 62(19), 4676-4684 (2006)
Synthesis of 7H-indolo [2, 3-c] quinolines: study of the Pd-catalyzed intramolecular arylation of 3-(2-bromophenylamino) quinolines under microwave irradiation.
Koubachi J, et al.
Tetrahedron, 66(10), 1937-1946 (2010)

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