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Merck
CN

123897

Sigma-Aldrich

1,1-二氯-2,2-双(4-氯苯基)乙烯

99%

别名:

4,4′-DDE

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About This Item

线性分子式:
(ClC6H4)2C=CCl2
CAS号:
分子量:
318.03
Beilstein:
1913355
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

方案

99%

表单

solid

mp

88-90 °C (lit.)

溶解性

ethanol: soluble

官能团

chloro

SMILES字符串

Clc1ccc(cc1)\C(=C(/Cl)Cl)c2ccc(Cl)cc2

InChI

1S/C14H8Cl4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8H

InChI key

UCNVFOCBFJOQAL-UHFFFAOYSA-N

基因信息

mouse ... Esr1(13982)
rat ... Ar(24208)

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应用

1,1-Dichloro-2,2-bis(4-chlorophenyl)ethane(DDE) has been used to study the ability of Pseudomonas acidovorans M3GY to transform DDE and its unchlorinated analog, 1,1-diphenylethylene (DPE).It has been used to investigate the role of incubation time, solvent type, yeast inoculum growth stage and concentration on the results of yeast assay for estrogenic compounds.

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - STOT RE 1 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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分析证书(COA)

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Willem Dhooge et al.
Analytical and bioanalytical chemistry, 386(5), 1419-1428 (2006-08-10)
In vitro assays are considered as the first step in a tiered approach to compound screening for hormonal activity. Although many new assays have been developed in recent years, little attention has been paid towards assay validation. Our objective was
A G Hay et al.
Applied and environmental microbiology, 64(6), 2141-2146 (1998-06-03)
1,1-Dichloro-2,2-bis(4-chlorophenyl)ethylene (DDE), a toxic breakdown product of 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT), has traditionally been viewed as a dead-end metabolite: there are no published reports detailing enzymatic ring fission of DDE by bacteria in either soil or pure culture. In this study, we
Fraser W Gaspar et al.
Environment international, 85, 163-167 (2015-09-24)
Although approximately 123 million people may be exposed to high levels of insecticides through the use of indoor residual spraying (IRS) for malaria control, few studies exist on indoor insecticide contamination due to IRS and its relationship with human exposure.
Jeanett L Tang-Péronard et al.
The American journal of clinical nutrition, 99(1), 5-13 (2013-10-25)
Chemicals with endocrine-disrupting abilities may act as obesogens and interfere with the body's natural weight-control mechanisms, especially if exposure occurs during prenatal life. We examined the association between prenatal exposure to polychlorinated biphenyls (PCBs) and p,p'-dichlorodiphenyldichloroethylene (DDE) and subsequent obesity
Mireia Gascon et al.
Environment international, 52, 51-65 (2013-01-08)
Disruption of developing immune and respiratory systems by early-life exposure to persistent organic pollutants (POPs) could result into reduced capacity to fight infections and increased risk to develop allergic manifestations later in life. To systematically review the epidemiologic literature on

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