122262
N,N,N′,N′-四(2-羟丙基)乙二胺
98%
别名:
Edetol, Entprol, (乙烯二腈)四-2-丙醇, Quadrol®
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线性分子式:
[CH3CH(OH)CH2]2NCH2CH2N[CH2CH(OH)CH3]2
化学文摘社编号:
分子量:
292.41
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-041-4
Beilstein/REAXYS Number:
1781143
MDL number:
产品名称
N,N,N′,N′-四(2-羟丙基)乙二胺, 98%
InChI key
NSOXQYCFHDMMGV-UHFFFAOYSA-N
InChI
1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3
SMILES string
CC(O)CN(CCN(CC(C)O)CC(C)O)CC(C)O
vapor pressure
1 mmHg ( 20 °C)
assay
98%
refractive index
n20/D 1.4812 (lit.)
bp
175-181 °C/0.8 mmHg (lit.)
density
1.013 g/mL at 25 °C (lit.)
Quality Level
Application
N,N,N′,N′-四（2-羟基丙基）乙二胺可用于：
- 作为单体合成共价交联、无定形形状记忆聚氨酯 (SMPU) 泡沫，用于生物医学应用，其中包括用于治疗缺血性中风的SMPU执行器、激光激活的血栓清除、可自部署的 SMP 神经元电极、血管支架、显微外科手术中的缝合线、眼部植入物、绷带、细胞操作和细胞疗法。
- 作为前体用于制备具有良好机械性质的热响应性自修复碳纤维增强聚合物（CFRP）。
- 作为交联剂，可形成具有生物相容性并支持神经细胞生长的水凝胶。水凝胶经过专门设计，可模拟细胞外基质 (ECM) 的特性，促进细胞增殖。在这种情况下，水凝胶的目的是充当细胞外基质（ECM）替代品，为细胞生长提供支持环境并引导细胞粘附和生长。这项研究调查了肽修饰通道促进神经组织工程和增强水凝胶支架内细胞增殖的潜力。
General description
N,N,N′,N′-四(2-羟丙基)乙二胺（也称为 Quadrol）是一种乙二胺基单体，用于生产聚氨酯涂料、粘合剂、化妆品和个人护理产品。由于其具有四个羟基，它可以充当螯合剂；由于其具有两个氨基，它可以充当交联剂。它被广泛用作聚合物和共聚物的构建单元，特别是那些设计用于可紫外线交联的聚氨酯聚合物、树枝状氨基聚合物、导电聚合物、油墨和涂料的聚合物和共聚物。此外，Quadrol还可用于树脂生产，以及表面活性剂、增塑剂和其他化学产品的制造。
Legal Information
Quadrol is a registered trademark of BASF Corporation
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
411.8 °F - closed cup
flash_point_c
211 °C - closed cup
ppe
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Yunseon Heo and Henry A. Sodano
Composites Science and Technology, 118, 244-250 (2015)
Gökhan Orhan et al.
Journal of hazardous materials, 112(3), 261-267 (2004-08-11)
An electrochemical method was applied for the recovery of copper both from the spent solutions and from the rinse waters of electroless copper plating baths, containing copper sulfate, formaldehyde, quadrol, and NaOH. Experiments were conducted in a rotating packed cell
Ona Gyliene et al.
Journal of hazardous materials, 175(1-3), 452-459 (2009-11-10)
Decontamination of solutions containing Cu(II) complexes with tartrate, glycine and quadrol (N,N,N'N'-tetrakis(2-hydroxypropyl)ethylenediamine) using metallic iron depends on pH and proceeds best in mildly acidic solutions. Cu(II) is completely removed from all solutions containing the ligands investigated. The degree of ligand
In vitro stimulation of macrophages by quadrol [N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine].
M V Bhide et al.
Journal of immunopharmacology, 7(3), 303-312 (1985-01-01)
Mouse peritoneal macrophages, when exposed to Quadrol [N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine] in vitro, show a dose dependent enhanced spreading over a four-hour period. In vitro Quadrol induced phagocytosis of polystyrene beads was found to be time and concentration dependent. The rate and extent
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