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Merck
CN

116025

Sigma-Aldrich

扁桃腈

technical grade

别名:

α-氰基苄醇, 杏仁腈, 苯甲氰醇

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About This Item

线性分子式:
C6H5CH(OH)CN
CAS号:
分子量:
133.15
Beilstein:
2207122
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

等级

technical grade

折射率

n20/D 1.530 (lit.)

沸点

170 °C (lit.)

溶解性

alcohol: freely soluble
chloroform: freely soluble
diethyl ether: freely soluble

密度

1.117 g/mL at 25 °C (lit.)

官能团

hydroxyl
nitrile
phenyl

SMILES字符串

OC(C#N)c1ccccc1

InChI

1S/C8H7NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H

InChI key

NNICRUQPODTGRU-UHFFFAOYSA-N

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应用

Mandelonitrile has been used to extract mandeloamide by the nitrilase variants.

象形图

Skull and crossbonesCorrosion

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

206.6 °F - closed cup

闪点(°C)

97 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Zhi-Jun Zhang et al.
Bioprocess and biosystems engineering, 34(3), 315-322 (2010-10-21)
A nitrilase gene from Alcaligenes sp. ECU0401 was cloned and overexpressed in Escherichia coli BL21 (DE3) in a soluble form. The encoded protein with a His₆-tag was purified to nearly homogeneity as revealed by SDS-PAGE with a molecular weight of
Aem Nuylert et al.
Chembiochem : a European journal of chemical biology, 18(3), 257-265 (2016-12-04)
A hydroxynitrile lyase from the passion fruit Passiflora edulis (PeHNL) was isolated from the leaves and showed high stability in biphasic co-organic solvent systems for cyanohydrin synthesis. Cyanohydrins are important building blocks for the production of fine chemicals and pharmaceuticals.
Hualei Wang et al.
BMC biotechnology, 13, 14-14 (2013-02-19)
A nitrilase-mediated pathway has significant advantages in the production of optically pure (R)-(-)-mandelic acid. However, unwanted byproduct, low enantioselectivity, and specific activity reduce its value in practical applications. An ideal nitrilase that can efficiently hydrolyze mandelonitrile to optically pure (R)-(-)-mandelic
Jennifer L Seffernick et al.
Journal of biotechnology, 143(1), 17-26 (2009-06-23)
Mining sequence data is increasingly important for biocatalysis research. However, when relying on sequence data alone, prediction of the reaction catalyzed by a specific protein sequence is often elusive, and substrate specificity is far from trivial. The present study demonstrated
Y Leong Yeow et al.
Journal of biotechnology, 111(1), 31-39 (2004-06-16)
The progress curves of conversion of racemic-mandelonitrile (R-MN) at different concentrations to benzaldehyde (BA) and hydrogen cyanide (HCN), catalyzed by S-hydroxynitrile lyase from Hevea brasiliensis, together with the enantiomeric excess curves of R-MN are converted into individual progress curves of

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