115312
N-ω-甲基色胺
99%
别名:
2-(吲哚-3-基)-N-甲基乙胺, 3-(2-[甲氨基]乙基)吲哚, 3-(2-甲基氨基乙基)吲哚, N-单甲基色胺, N10-甲基色胺, 甲基色胺
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关于此项目
经验公式（希尔记法）:
C11H14N2
化学文摘社编号:
分子量:
174.24
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
99%
表单
solid
mp
87-89 °C (lit.)
官能团
amine
SMILES字符串
CNCCc1c[nH]c2ccccc12
InChI
1S/C11H14N2/c1-12-7-6-9-8-13-11-5-3-2-4-10(9)11/h2-5,8,12-13H,6-7H2,1H3
InChI key
NCIKQJBVUNUXLW-UHFFFAOYSA-N
应用
N-ω-甲基色胺已用于制备N-乙酰基-α−甲基色胺。
N-ω-甲基色胺已用于通过钩藤(U. tomentosa)蛋白提取物生物合成dolichantoside。
作为反应物用于制备：
- Manzamine类似物用于控制神经炎症和脑部感染
- 血清素4受体(5-HT4)受体激动剂
- Glypetelotine，一种含硫的吲哚生物碱
- 周期蛋白依赖性激酶(CDK4)的选择性抑制剂
- 人速激肽NK-2受体拮抗剂
- 酪氨酸特异性蛋白激酶pp60c-src SH2结构域的抑制剂
包装
无底玻璃瓶。内含物装在锥底内插管中。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
R W Walker et al.
Journal of chromatography, 289, 223-229 (1984-04-27)
A capillary column gas-liquid chromatography selected ion monitoring-based method was developed for the measurement of [13C,15N]N-methyltryptamine ( NMT ) in human urine. The method was employed to establish the extent of conversion of [13C,15N]tryptamine to the correspondingly labeled NMT in
Luigi Servillo et al.
Journal of agricultural and food chemistry, 60(37), 9512-9518 (2012-09-11)
The occurrence of N-methylated tryptamine derivatives in bergamot plant (Citrus bergamia Risso et Poit) is reported for the first time. Interestingly, the most abundant of these substances is N,N,N-trimethyltryptamine, which has not been previously identified in any citrus plant. The
T J Williams et al.
European journal of pharmacology, 245(3), 197-201 (1993-05-15)
The binding of [3H]5-hydroxytryptamine (5-HT) to rat enteric membranes was inhibited by the inclusion of 5-HT 2-methyl-5-HT, 5-hydroxytryptophan, N,N,N-triethyltryptamine and 2-Br-N,N-diethyltryptamine in the incubation buffer. In contrast, tryptamine, 5-methoxytryptamine and 2-methyl-N,N-diethyltryptamine enhanced binding. Ascorbate and dithiothreitol facilitated and reduced binding
Strictosidine-related enzymes involved in the alkaloid biosynthesis of Uncaria tomentosa root cultures grown under oxidative stress.
Vera-Reyes I, Huerta-Heredia AA, Ponce-Noyola T, et al.
Biotechnology Progress, doi:10-doi:10 (2013)
W J VandenHeuvel et al.
Journal of chromatographic science, 21(3), 119-124 (1983-03-01)
This report focuses on recent applications of capillary column GLC to the analysis of drugs and metabolites, other xenobiotics, natural products, and environmental contaminants in samples of biological origin. The increasing use of selected ion monitoring, combined with stable isotope
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