115169
四甲基硫脲
98%
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关于此项目
线性分子式:
(CH3)2NCSN(CH3)2
化学文摘社编号:
分子量:
132.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-488-0
Beilstein/REAXYS Number:
1744916
MDL number:
Assay:
98%
Form:
solid
InChI key
MNOILHPDHOHILI-UHFFFAOYSA-N
InChI
1S/C5H12N2S/c1-6(2)5(8)7(3)4/h1-4H3
SMILES string
CN(C)C(=S)N(C)C
assay
98%
form
solid
bp
245 °C (lit.)
mp
75-77 °C (lit.)
storage temp.
2-8°C
Quality Level
General description
四甲基硫脲分子表现出具有氢键堆积较弱的晶体学上双重对称性，使分子可连接形成层。
Application
四甲基硫脲可与四甲基硒脲形成BF3加合物。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Allen Mambanda et al.
Dalton transactions (Cambridge, England : 2003), 39(15), 3595-3608 (2010-04-01)
The rate of displacement of the aqua ligands by three neutral nucleophiles (Nu) of different steric demands, namely thiourea (tu), N,N'-dimethylthiourea (dmtu) and N,N,N',N'-tetramethylthiourea (tmtu) and an anionic nucleophile (I(-)) in complexes of the form [{Pt(H(2)O)}(2)(N,N,N',N'-tetrakis(2-pyridylmethyl)-N(CH(2))(n)N](CF(3)SO(3))(4), n = 2 (En);
Alexius Freyberger et al.
Toxicology, 217(2-3), 169-175 (2005-11-22)
N,N,N',N'-Tetramethylthiourea (TMTU) is a rat goitrogen inducing thyroid hyperplasia, hypertrophy, and tumor formation. Little is known about the exact underlying mechanism of action. As thyroid peroxidase (TPO) and type I iodothyronine deiodinase (ID-I) have been established as targets of goitrogenic
Jiqin Liu et al.
Molecular immunology, 45(15), 3984-3989 (2008-07-29)
N-Acetylcysteine (NAC) has been widely used as an antioxidant in research, however, it has also been found to reduce the binding of TNF to its receptor independent of its antioxidative role. In this study, we investigated the effect of NAC
Y Usson et al.
Journal of neurocytology, 17(5), 639-648 (1988-10-01)
The proliferation of Schwann cells in the sciatic nerve of chick was studied from day 11 to day 27 of development in control and thyroid-deficient embryos. Hypothyroidism was induced by tetramethylthiourea injection on days 8 and 19 of incubation. The
Andrew Churg et al.
Toxicology and applied pharmacology, 208(1), 37-45 (2005-09-17)
Air pollution particles (PM) are known to elicit an acute inflammatory response in vivo that is mediated in part through PM-induced activation of the NF-kappaB signaling pathway. Many of the details of this process and particularly where in the cell
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