跳转至内容
Merck
CN

11373

Sigma-Aldrich

HATU

≥98.0% (CHN), for peptide synthesis

别名:

1-[双(二甲基氨基)亚甲基]-1H-1,2,3-三唑[4,5-b]吡啶-3-氧化物六氟磷酸酯, N-[(二甲基氨基)-1H-1,2,3-三唑-[4,5-b]吡啶-1-亚甲基]-N-甲基甲铵六氟磷酸酯- N-氧化物, HATU

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C10H15F6N6OP
分子量:
380.23
MDL编号:
UNSPSC代码:
12352302
PubChem化学物质编号:
NACRES:
NA.22

产品名称

HATU, ≥98.0% (CHN)

质量水平

方案

≥98.0% (CHN)

表单

solid

反应适用性

reaction type: Coupling Reactions

mp

183-185 °C (lit.)
183-188 °C (dec.)

应用

peptide synthesis

官能团

amine

储存温度

2-8°C

SMILES字符串

F[P-](F)(F)(F)(F)F.CN(C)[C+](N(C)C)n1n[n+]([O-])c2ncccc12

InChI

1S/C10H15N6O.F6P/c1-13(2)10(14(3)4)15-8-6-5-7-11-9(8)16(17)12-15;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1

InChI key

FKBFHOSFPRWJNV-UHFFFAOYSA-N

正在寻找类似产品? 访问 产品对比指南

应用

用作以下反应的试剂:
Aurora A激酶抑制剂的合成
人血浆中的D-和L-酸对映体的HPLC测定
酰胺键形成反应

用作以下反应的催化剂:
选择性酰化反应
硒环化-氧化脱硒连续反应

其他说明

最近研究表明,这种偶联剂的晶体和溶液结构是胍的N-氧化物形式,而不是脲化合物;固相肽合成的优势偶联剂。

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Resp. Sens. 1 - Skin Sens. 1A

补充剂危害

储存分类代码

4.1A - Other explosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

The uronium/guanidinium Peptide coupling reagents: finally the true uronium salts.
Louis A Carpino et al.
Angewandte Chemie (International ed. in English), 41(3), 441-445 (2002-12-20)
L. Carpino et al.
Journal of the Chemical Society. Chemical Communications, 201-201 (1994)
Qingxin Chen et al.
Journal of virology, 94(19) (2020-07-17)
Adeno-associated virus (AAV) has proven to be a promising candidate for gene therapy due to its nonpathogenic nature, ease of production, and broad tissue tropism. However, its transduction capabilities are not optimal due to the interaction with various host factors
Mazen Jamous et al.
Nuclear medicine and biology, 41(6), 464-470 (2014-05-02)
The gastrin-releasing peptide receptor (GRPR) was shown to be expressed with high density on several types of cancers. Radiolabeled peptides for imaging and targeted radionuclide therapy have been developed. In this study, we evaluated the potential of statine-based bombesin antagonists
Anna K Lee et al.
Molecular cell, 79(4), 645-659 (2020-07-22)
Stress granules (SGs) are membrane-less ribonucleoprotein condensates that form in response to various stress stimuli via phase separation. SGs act as a protective mechanism to cope with acute stress, but persistent SGs have cytotoxic effects that are associated with several

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门