109630
1-羟基-2-萘甲酸
≥97.0%
别名:
α-羟基萘甲酸
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线性分子式:
HOC10H6CO2H
化学文摘社编号:
分子量:
188.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-674-0
Beilstein/REAXYS Number:
974438
MDL number:
Assay:
≥97.0%
InChI key
SJJCQDRGABAVBB-UHFFFAOYSA-N
InChI
1S/C11H8O3/c12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h1-6,12H,(H,13,14)
SMILES string
OC(=O)c1ccc2ccccc2c1O
assay
≥97.0%
mp
195-200 °C (dec.) (lit.)
solubility
alcohol: freely soluble, benzene: freely soluble, cold water: insoluble, diethyl ether: freely soluble
functional group
carboxylic acid
Quality Level
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General description
1-Hydroxy-2-naphthoic acid is produced by the transformation of phenanthrene by NCIB 9816 clones.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
K Hanna et al.
Chemosphere, 70(2), 178-186 (2007-08-11)
The adsorption of naphthoic acids to iron oxides and hydroxides influences strongly their mobility in soils and sediments. Sorption of 1-hydroxy-2-naphthoic acid (HNA) to three iron oxides was examined over a wide range of conditions (pH, ionic strength, sorbate and
Marta Ferraroni et al.
Journal of structural biology, 177(2), 431-438 (2011-12-14)
The crystallographic structures of the adducts of salicylate 1,2-dioxygenase (SDO) with substrates salicylate, gentisate and 1-hydroxy-2-naphthoate, obtained under anaerobic conditions, have been solved and analyzed. This ring fission dioxygenase from the naphthalenesulfonate-degrading bacterium Pseudaminobacter salicylatoxidans BN12, is a homo-tetrameric class
Mario Cazzola et al.
Clinical pharmacokinetics, 41(1), 19-30 (2002-02-05)
Salmeterol is an inhaled long-acting selective beta(2)-adrenoceptor agonist that is commercially available as the xinafoate (1-hydroxy-2-naphthoic acid) salt of the racemic mixture of the two optical isomers, (R)- and (S)-, of salmeterol. It acts locally in the lung through action
Marta Ferraroni et al.
The FEBS journal, 280(7), 1643-1652 (2013-02-07)
The salicylate 1,2-dioxygenase (SDO) from the bacterium Pseudaminobacter salicylatoxidans BN12 is a versatile gentisate 1,2-dioxygenase (GDO) that converts both gentisate (2,5-dihydroxybenzoate) and various monohydroxylated substrates. Several variants of this enzyme were rationally designed based on the previously determined enzyme structure
Bibiana M Coppotelli et al.
Microbial ecology, 59(2), 266-276 (2009-07-18)
The present study describes the phenanthrene-degrading activity of Sphingomonas paucimobilis 20006FA and its ability to promote the bioavailability of phenanthrene. S. paucimobilis 20006FA was isolated from a phenanthrene-contaminated soil microcosm. The strain was able to grow in liquid mineral medium
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