所有图片(1)
About This Item
经验公式(希尔记法):
C6H11NaO3S
CAS号:
分子量:
186.20
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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方案
≥98.0% (T)
表单
solid
杂质
≤1% water
SMILES字符串
[Na+].[O-]S(=O)(=O)C1CCCCC1
InChI
1S/C6H12O3S.Na/c7-10(8,9)6-4-2-1-3-5-6;/h6H,1-5H2,(H,7,8,9);/q;+1/p-1
InChI key
DIIKAKPJAGLSOD-UHFFFAOYSA-M
一般描述
Sodium cyclohexanesulfonate is a white to faintly beige powder to fine crystals with lump.
应用
Sodium cyclohexanesulfonate was used to study the influence of various hydrophobic ionic excipients on viscosity of concentrated solutions of therapeutic proteins. It was used as an ionic hydrophobic excipient that substantially decrease the viscosity of concentrated (300-400 mg/mL) aqueous solutions of bovine serum albumin and γ-globulin.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Wei Du et al.
Biotechnology and bioengineering, 108(3), 632-636 (2011-01-20)
Reducing viscosities of concentrated solutions of therapeutic proteins is important for their subcutaneous and intravenous delivery. Although inorganic salts and optimizing the pH were previously reported to dramatically lower the viscosity of a monoclonal antibody solution, herein we have determined
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