推荐产品
质量水平
检测方案
≥98%
mp
226-229 °C (lit.)
溶解性
H2O: soluble 1g in 290ml
acetone: soluble 1g in 12ml
alcohol: soluble 1g in 31ml
boiling water: soluble 1g in 25ml
glycerol: soluble 1g in 50ml
alcohol: very slightly soluble
chloroform: slightly soluble
diethyl ether: slightly soluble
SMILES字符串
O=C1NS(=O)(=O)c2ccccc12
InChI
1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
InChI key
CVHZOJJKTDOEJC-UHFFFAOYSA-N
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应用
高效液相色谱法采用糖精对乙酰磺胺酸钾、糖精和阿斯巴甜进行同时分离和测定 。用于大鼠的甜味偏好测试 。
生化/生理作用
N-甲基-N′-硝基-N-亚硝基胍后给予糖精促进大鼠肿瘤的发展。
哺乳动物的甜促味剂。有人提出，果蝇具有葡萄糖特异性甘油味觉受体结合位点。
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Anne Marie Vinggaard et al.
Toxicological sciences : an official journal of the Society of Toxicology, 85(2), 886-897 (2005-03-25)
Prochloraz is a commonly used fungicide that has shown multiple mechanisms of action in vitro. It antagonizes the androgen and the estrogen receptors, agonizes the Ah receptor, and inhibits aromatase activity. In vivo prochloraz acts antiandrogenically in the Hershberger assay
M Takahashi et al.
Gan, 75(6), 494-501 (1984-06-01)
Sodium chloride, saccharin sodium, phenobarbital sodium and aspirin were tested for tumor-promoting activity in the glandular stomach of rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) coupled with administration of a high salt diet. Male outbred Wistar rats were given MNNG in
Hellmuth Lilienthal et al.
Toxicology, 311(1-2), 52-60 (2013-02-14)
Many chemicals are known to exhibit endocrine activity and affect reproductive functions in vertebrates and invertebrates. Endocrine effects include influences on sexual differentiation of the brain during development and reproductive and non-reproductive behavior in adult offspring. We previously demonstrated that
Katharine J Tuerke et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(40), 13709-13717 (2012-10-05)
A taste associated with emetic drugs produces conditioned disgust reactions in rats (predominantly gaping), unlike nonemetic drugs that can still produce conditioned taste avoidance but not conditioned disgust. That difference suggests nausea is a prerequisite for learning disgust reactions to
Rino Ragno et al.
Journal of medicinal chemistry, 50(6), 1241-1253 (2007-02-28)
The screening of the inhibition capabilities of dye-like small molecules from a focused library against both human PRMT1 and Aspergillus nidulans RmtA is reported as well as molecular modeling studies (homology modeling, molecular docking, and 3-D QSAR) of the catalytic
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