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Merck
CN

108995

Sigma-Aldrich

巯基乙酸甲酯

95%

别名:

硫代乙醇酸甲酯

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About This Item

线性分子式:
HSCH2CO2CH3
CAS号:
分子量:
106.14
Beilstein:
506259
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

方案

95%

反应适用性

reagent type: ligand
reaction type: [1,2]-Wittig Rearrangement

折射率

n20/D 1.466 (lit.)

沸点

42-43 °C/10 mmHg (lit.)

密度

1.187 g/mL at 25 °C (lit.)

官能团

ester
thiol

SMILES字符串

COC(=O)CS

InChI

1S/C3H6O2S/c1-5-3(4)2-6/h6H,2H2,1H3

InChI key

MKIJJIMOAABWGF-UHFFFAOYSA-N

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相关类别

一般描述

巯基乙酸甲酯与抗肿瘤抗生素新抑癌蛋白的非蛋白成分反应形成 1:1 加合物 。它与异硫氰酸盐反应生成罗丹宁

应用

巯基乙酸甲酯用于制备:
  • 3-甲氧羰基-4-氧四氢硫代吡喃, 2-和4-甲氧羰基-3-氧四氢噻吩
  • 巯基乙酸甲酯和氨基乙硫醇修饰的金纳米棒
制备硫醇有机催化剂用于通过可见光催化影响苄基醚C-H键的直接芳基化

光氧化还原催化下C–H键有机催化活化的一般策略:苄基醚的直接芳基化

产品适配我们的光反应器系列:包括Penn PhD (Z744035) & SynLED 2.0 (Z744080)

象形图

FlameSkull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

132.8 °F - closed cup

闪点(°C)

56 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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T Kusakabe et al.
Biochemistry, 34(31), 9944-9950 (1995-08-08)
A double-stranded DNA cleavage mechanism by a novel enediyne type antitumor antibiotic, dynemicin A, has been investigated through sequence-dependent strand breakage of a series of duplexes containing a single nucleotide gap. We found that (1) dynemicin A breaks specifically at
Samantha Seng et al.
Physical chemistry chemical physics : PCCP, 20(29), 19416-19423 (2018-06-28)
Understanding the formation and transformation of sulphur-rich particles is of prime importance since they contribute to the global atmospheric sulphur budget. In this work, we performed a series of experiments on a photoactive organosulphur compound namely, methyl thioglycolate, as a
Yuling Xiao et al.
Theranostics, 2(8), 757-768 (2012-08-24)
A multifunctional gold nanorod (GNR)-based nanoplatform for targeted anticancer drug delivery and positron emission tomography (PET) imaging of tumors was developed and characterized. An anti-cancer drug (i.e., doxorubicin (DOX)) was covalently conjugated onto PEGylated (PEG: polyethylene glycol) GNR nanocarriers via
M K Vadnere et al.
Journal of medicinal chemistry, 29(9), 1714-1720 (1986-09-01)
The reaction of methyl mercaptoacetate (5) with phenyl-p-benzoquinone (6) or 5-p-benzoquinonyl-3',5'-di-O-acetyl-2'-deoxyuridine (10) resulted in the formation of the three possible adducts to the quinone rings of 6 and 10; an additional product in the reaction with 10 was the unsubstituted
W A LaMarr et al.
Proceedings of the National Academy of Sciences of the United States of America, 95(1), 102-107 (1998-02-21)
DNA superhelical tension, an important feature of genomic organization, is known to affect the interactions of intercalating molecules with DNA. However, the effect of torsional tension on nonintercalative DNA-binding chemicals has received less attention. We demonstrate here that the enediyne

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