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质量水平
方案
97%
mp
159-161 °C (lit.)
溶解性
H2O: soluble 50 mg/mL
官能团
amine
hydrazine
SMILES字符串
NNC(=O)c1cccnc1
InChI
1S/C6H7N3O/c7-9-6(10)5-2-1-3-8-4-5/h1-4H,7H2,(H,9,10)
InChI key
KFUSANSHCADHNJ-UHFFFAOYSA-N
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一般描述
异烟碱酰肼是一种杂环化合物，可用于合成席夫碱。
应用
烟酰肼用于腙文库形成 。用于研究辣根过氧化物酶对异烟酸酰肼（异烟肼）的氧化作用 。
生化/生理作用
烟酰肼是过氧化物酶的抑制剂 。形成具有较强生物活性的固体金属配合物 。
制备说明
烟酰肼溶于水中，浓度为 50 mg/mL，形成澄清、无色溶液。
警示用语：
Warning
危险声明
预防措施声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
V Goral et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(4), 1347-1352 (2001-02-15)
Dynamic combinatorial libraries are mixtures of compounds that exist in a dynamic equilibrium and can be driven to compositional self adaptation via selective binding of a specific assembly of certain components to a molecular target. We present here an extension
H A Shoeb et al.
Antimicrobial agents and chemotherapy, 27(3), 399-403 (1985-03-01)
Oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase at the expense of H2O2 yielded reactive species which were able to reduce nitroblue tetrazolium and bleach p-nitrosodimethylaniline. Nicotinic acid hydrazide oxidation did not cause these effects. At slightly alkaline pH
Thermo-chemical behavior of solid nicotinic hydrazide metal complexes in correlation with their stoichiometry.
Sekkina MM and El-Azm MG.
Thermochimica Acta, 77(1), 211-218 (1984)
Synthesis, spectroscopic characterization, and crystal structures of Schiff bases derived from nicotinic hydrazide
Diouf F, et al.
IOSR journal of applied chemistry, 1 serie II (2022)
B Toth
Oncology, 38(2), 106-109 (1981-01-01)
Nicotinic acid hydrazide was administered as a 0.125% solution in drinking water continuously for life from 6 weeks of age to randomly bred Swiss albino mice. As a result of treatment, the lung tumor incidence rose from 25 to 76%
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