107425
烟酰肼
97%
别名:
烟酸酰肼
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关于此项目
经验公式（希尔记法）:
C6H7N3O
化学文摘社编号:
分子量:
137.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-041-0
Beilstein/REAXYS Number:
119299
MDL number:
Assay:
97%
InChI key
KFUSANSHCADHNJ-UHFFFAOYSA-N
InChI
1S/C6H7N3O/c7-9-6(10)5-2-1-3-8-4-5/h1-4H,7H2,(H,9,10)
SMILES string
NNC(=O)c1cccnc1
assay
97%
Quality Level
mp
159-161 °C (lit.)
solubility
H2O: soluble 50 mg/mL
functional group
amine, hydrazine
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General description
异烟碱酰肼是一种杂环化合物，可用于合成席夫碱。
Application
烟酰肼用于腙文库形成 。用于研究辣根过氧化物酶对异烟酸酰肼（异烟肼）的氧化作用 。
Biochem/physiol Actions
烟酰肼是过氧化物酶的抑制剂 。形成具有较强生物活性的固体金属配合物 。
Preparation Note
烟酰肼溶于水中，浓度为 50 mg/mL，形成澄清、无色溶液。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
H A Shoeb et al.
Antimicrobial agents and chemotherapy, 27(3), 399-403 (1985-03-01)
Oxidation of isonicotinic acid hydrazide (isoniazid) by horseradish peroxidase at the expense of H2O2 yielded reactive species which were able to reduce nitroblue tetrazolium and bleach p-nitrosodimethylaniline. Nicotinic acid hydrazide oxidation did not cause these effects. At slightly alkaline pH
Thermo-chemical behavior of solid nicotinic hydrazide metal complexes in correlation with their stoichiometry.
Sekkina MM and El-Azm MG.
Thermochimica Acta, 77(1), 211-218 (1984)
V Goral et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(4), 1347-1352 (2001-02-15)
Dynamic combinatorial libraries are mixtures of compounds that exist in a dynamic equilibrium and can be driven to compositional self adaptation via selective binding of a specific assembly of certain components to a molecular target. We present here an extension
Nives Galić et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 107, 263-270 (2013-02-26)
Structural forms of aroylhydrazones derived from nicotinic acid hydrazide have been studied in the solid state by FT-IR spectroscopy and in solution by NMR, UV-Vis and ATR spectroscopy. The studied compounds were N'-benzylidene-3-pyridinecarbohydrazide (1), N'-(2,4-dihydroxyphenylmethylidene)-3-pyridinecarbohydrazide (2), N'-(5-chloro-2-hydroxyphenylmethylidene)-3-pyridinecarbohydrazide (3), and N'-(3,5-dichloro-2-hydroxymethoxyphenylmethylidene)-3-pyridinecarbohydrazide
Synthesis, spectroscopic characterization, and crystal structures of Schiff bases derived from nicotinic hydrazide
Diouf F, et al.
IOSR journal of applied chemistry, 1 serie II (2022)
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