推荐产品
质量水平
检测方案
98%
形式
solid
mp
>300 °C (lit.)
SMILES字符串
Brc1ncnc2nc[nH]c12
InChI
1S/C5H3BrN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
InChI key
CTGFGRDVWBZYNB-UHFFFAOYSA-N
一般描述
6-Bromopurine enhances the carcinostatic activity of azaserine in a test system employing ascites cell forms of sarcoma 180 and Ehrlich carcinoma in vivo. 6-bromopurine nucleosides are excellent substrates for substitution reactions with N-, O-, and S-containing nucleophiles in polar solvents.
应用
6-Bromopurine was used in the synthesis of 6-halopurine alkynes and corresponding triazole derivatives. 6-Bromopurine was used in the synthesis and chemical characterization of 2,3,4,5-tetrahydro-1,5-benzoxazepines-3-ol.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Eva Galante et al.
Molecules (Basel, Switzerland), 18(5), 5335-5347 (2013-05-15)
2-[¹⁸F]Fluoroethyl azide ([¹⁸F]FEA) can readily be obtained by nucleophilic substitution of 2-azidoethyl-4-toluenesulfonate with [¹⁸F]fluoride (half-life 110 min), and has become widely used as a reagent for 'click' labeling of PET tracers. However, distillation of [18F]FEA is typically required, which is
Synthesis, unambiguous chemical characterization, and reactivity of 2, 3, 4, 5-tetrahydro-1, 5-benzoxazepines-3-ol.
Garcia-Rubino ME, et al.
Royal Society of Chemistry Advances, 2(33), 12631-12635 (2012)
Comparison of some biologgical and biochemical properties of 6-bromopurine and 6-iodopurine.
A C SARTORELLI et al.
Biochemical pharmacology, 11, 1017-1024 (1962-11-01)
E A Véliz et al.
The Journal of organic chemistry, 66(25), 8592-8598 (2001-12-12)
Surprisingly facile direct substitution reactions with acetyl-protected 6-bromopurine nucleosides are described. Included in the series of bromonucleosides studied is the guanosine derivative N(2)-2',3',5'-tetraacetyl-6-bromopurine ribonucleoside, the synthesis of which is reported here for the first time. Brominated nucleosides had not previously
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门