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质量水平
方案
99%
表单
solid
mp
117-120 °C (lit.)
官能团
carboxylic acid
nitro
SMILES字符串
OC(=O)Cc1cccc(c1)[N+]([O-])=O
InChI
1S/C8H7NO4/c10-8(11)5-6-2-1-3-7(4-6)9(12)13/h1-4H,5H2,(H,10,11)
InChI key
WUKHOVCMWXMOOA-UHFFFAOYSA-N
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一般描述
3-Nitrophenylacetic acid is obtained by mild oxidation of 4-amino phenylacetic acid using potassium peroxymonosulfate as oxidizing agent in acetone.
应用
3-Nitrophenylacetic acid was used to study photodecarboxylation of nitrophenylacetate ions in aqueous solution. 3-Nitrophenylacetic acid was used in study to synthesize an azobenzene amino acid, having potent use as photo-inducible conformational switch in polypeptides.
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
Photodecarboxylation of nitrophenylacetate ions.
Margerum JD and Petrusis CT.
Journal of the American Chemical Society, 91(10), 2467-2472 (1969)
A mild oxidation of aromatic amines.
Webb KS and Seneviratne S.
Tetrahedron Letters, 36(14), 2377-2378 (1995)
Andreas Aemissegger et al.
Nature protocols, 2(1), 161-167 (2007-04-03)
The synthesis of an azobenzene amino acid (aa) for use as a photo-inducible conformational switch in polypeptides is described. The compound can be easily incorporated into an aa sequence by solid-phase peptide synthesis using standard 9-fluorenylmethoxycarbonyl methods. A reversible conformational
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