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Merck
CN

100919

Sigma-Aldrich

N-(4-溴丁基)邻苯二甲酰亚胺

98%

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别名:
1-Phthalimido-4-bromobutane, 2-(4-Bromobutyl)-2,3-dihydro-1H-isoindole-1,3-dione, 2-(4-Bromobutyl)phthalimide, 4-Bromobutylphthalimide
经验公式(希尔记法):
C12H12BrNO2
CAS号:
分子量:
282.13
Beilstein:
164119
EC 号:
MDL编号:
UNSPSC代码:
12352111
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

98%

反应适用性

reagent type: cross-linking reagent
reagent type: linker

mp

76-80 °C (lit.)

官能团

bromo

聚合物结构设计

functionality: heterobifunctional

SMILES字符串

O=C1N(CCCCBr)C(C2=CC=CC=C21)=O

InChI

1S/C12H12BrNO2/c13-7-3-4-8-14-11(15)9-5-1-2-6-10(9)12(14)16/h1-2,5-6H,3-4,7-8H2

InChI key

UXFWTIGUWHJKDD-UHFFFAOYSA-N

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应用

N-(4-Bromobutyl)phthalimide can be used to synthesize:
  • Biologically important N4,N9-disubstituted 4,9-diaminoacridine derivatives.
  • Imidazo[4,5-b]pyridine derivatives applicable in the preparation of ketolide antibiotics.
  • Calix[4]arene and thiacalix[4]arene-based oxamate ligands.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Synthesis of multivalent oxamate ligands based on calix [4] arene and thiacalix [4] arene backbones in 1, 3-Alternate conformation
Noamane MH, et al.
Tetrahedron, 73, 4259-4264 (2017)
Synthesis of derivatives of imidazo [4,5-b] pyridine: Novel sulfur contained side chains for macrolide antibiotics
Liu L, et al.
Chinese Chemical Letters = Zhongguo Hua Xue Kuai Bao, 19, 1-4 (2008)
Zhanhui Wang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 971, 10-13 (2014-09-28)
The application of antibodies to small molecules in the field of bioanalytics requires antibodies with stable biological activity and high purity; thus, there is a growing interest in developing rapid, inexpensive and effective procedures to obtain such antibodies. In this
Development of a synthetic route towards N4, N9-disubstituted 4, 9-diaminoacridines: On the way to multi-stage antimalarials
Fonte M, et al.
Tetrahedron Letters, 60, 1166-1169 (2019)

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