推荐产品
质量水平
检测方案
≥99%
形式
solid
mp
209-212 °C (subl.) (lit.)
SMILES字符串
C1[C@H]2C[C@H]3C[C@@H]1C[C@@H](C2)C3
InChI
1S/C10H16/c1-7-2-9-4-8(1)5-10(3-7)6-9/h7-10H,1-6H2/t7-,8+,9-,10+
InChI key
ORILYTVJVMAKLC-YNFQOJQRSA-N
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应用
金刚烷是金刚烷胺、美金刚、沙格列汀和维格列汀等多种药物重要化合物的结构骨架。 用于合成类卡宾反应的基于金刚烷的四羧酸二铑催化剂。也可作为纳米金刚石薄膜成核的种子材料。
The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivatives.
Lukas Wanka et al.
Chemical reviews, 113(5), 3516-3604 (2013-02-26)
Vlad Badilita et al.
PloS one, 7(8), e42848-e42848 (2012-09-01)
This article describes the development and testing of the first automatically microfabricated probes to be used in conjunction with the magic angle coil spinning (MACS) NMR technique. NMR spectroscopy is a versatile technique for a large range of applications, but
Adamantane?a lead structure for drugs in clinical practice.
Spilovska K, et al.
Current Medicinal Chemistry, 23(29), 3245-3266 (2016)
Louis H Miller et al.
Nature medicine, 19(2), 156-167 (2013-02-08)
Plasmodium falciparum malaria, an infectious disease caused by a parasitic protozoan, claims the lives of nearly a million children each year in Africa alone and is a top public health concern. Evidence is accumulating that resistance to artemisinin derivatives, the
Dirhodium tetracarboxylate derived from adamantylglycine as a chiral catalyst for carbenoid reactions.
Reddy R P, et al.
Organic Letters, 8(16), 3437-3440 (2006)
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