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线性分子式:
NH2CH2CH2OSO3H
化学文摘社编号:
分子量:
141.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
213-135-7
MDL number:
Beilstein/REAXYS Number:
1704079
产品名称
2-氨基乙基硫酸氢酯, ≥98.0% (T)
SMILES string
NCCOS(O)(=O)=O
NCCOS(O)(=O)=O
InChI key
WSYUEVRAMDSJKL-UHFFFAOYSA-N
InChI
1S/C2H7NO4S/c3-1-2-7-8(4,5)6/h1-3H2,(H,4,5,6)
assay
≥98.0% (T)
mp
277 °C (dec.) (lit.)
functional group
amine
Quality Level
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
D V Coscina et al.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 16(6), 425-433 (1992-06-01)
To explore recent suggestions that genetically obese Zucker rats show less anorexia when brain gamma-aminobutyric acid (GABA) is elevated, obese vs. lean littermates received 100, 50 and 0 micrograms of the GABA-transaminase inhibitor, ethanolamine-O-sulfate (EOS), intra-cisternally in a longitudinal design
R Horton et al.
General pharmacology, 19(3), 403-405 (1988-01-01)
1. Oral administration of the GABA transaminase inhibitor ethanolamine-O-sulphate (EOS, 5 mg/ml in drinking water) to rats for 14 days suppressed food intake by 24%, but reduced weight gain by over 35%. 2. Thus, feed efficiency (g gain/MJ eaten) was
J Semba et al.
Neuropsychobiology, 21(3), 152-156 (1989-01-01)
We carried out the forced swimming test in mice to investigate the antidepressant potentials of GABA transaminase (GABA-T) inhibitors including aminooxyacetic acid, ethanolamine-O-sulfate, gamma-vinyl GABA (GVG) and valproic acid (VPA). In acute experiments only GVG reduced immobility. Following chronic oral
D V Coscina et al.
Pharmacology, biochemistry, and behavior, 32(1), 275-281 (1989-01-01)
Intracisternal (IC) injection of the GABA-transaminase inhibitor, ethanolamine-O-sulfate (EOS), has been previously shown to induce dose-dependent anorexia in normal rats as well as to reverse overeating in several rodent models of acute and chronic hyperphagia. To determine if such anorexia
M Qume et al.
Biochemical pharmacology, 52(9), 1355-1363 (1996-11-08)
The inhibitory neurotransmitter gamma-aminobutyric acid (GABA) is not solely located in the CNS, it and the enzymes responsible for its synthesis (glutamic acid decarboxylase, GAD, EC 4.1.1.15) and catabolism (GABA-transaminase, GABA-T, EC 2.6.1.19) are also present in non-neuronal organs. Following
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