TPM1
tropomyosin 1 (alpha)
别名:
C15orf13, CMD1Y, CMH3, HTM-alpha, LVNC9, TMSA
物种:
Human TPM1 (7168), Mouse Tpm1 (22003), Rat Tpm1 (24851), chicken TPM1 (396366), Zebrafish tpm1 (393908), domestic cat TPM1 (101091450), dog TPM1 (478332), naked mole-rat Tpm1 (101714552), sheep TPM1 (100145865), domestic guinea pig Tpm1 (100717160)
UniProtKB ID:
基因ID:
- Human(7168) Summary: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]
- Mouse(22003) tropomyosin 1, alpha
- Rat(24851) tropomyosin 1, alpha
- chicken(396366) tropomyosin 1 (alpha)
- Zebrafish(393908) tropomyosin 1 (alpha)
- domestic cat(101091450) tropomyosin 1 (alpha)
- dog(478332) tropomyosin 1 (alpha)
- naked mole-rat(101714552) tropomyosin 1 (alpha)
- sheep(100145865) tropomyosin 1 (alpha)
- domestic guinea pig(100717160) tropomyosin 1 (alpha)
- cow(281544) tropomyosin 1 (alpha)
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Antibodies
货号
说明
物种反应性
应用
Anti-Tropomyosin antibody produced in rabbit, whole antiserum,
物种反应性
chicken
应用
immunofluorescence
western blot
western blot
Anti-Tropomyosin Antibody, clone 15D12.2, clone 15D12.2, from mouse,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-Tropomyosin Antibody, Smooth Muscle, serum, Chemicon®,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-TPM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Tropomyosin-1 Antibody, clone 7F8B8, clone 7F8B8, from rat,
物种反应性
human, mouse
应用
immunocytochemistry
western blot
western blot