RAD51
RAD51 recombinase
别名:
BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA
物种:
Human RAD51 (5888), Mouse Rad51 (19361), Rat Rad51 (499870), domestic cat RAD51 (101089015), domestic guinea pig Rad51 (100716391), Domestic Rabbit RAD51 (100008661), naked mole-rat Rad51 (101715048), chicken RAD51 (396086), Zebrafish rad51 (406487), Thale Cress RAD51 (832208) ...展开
UniProtKB ID:
基因ID:
- Human(5888) Summary: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
- Mouse(19361) RAD51 homolog
- Rat(499870) RAD51 recombinase
- domestic cat(101089015) RAD51 homolog (S. cerevisiae)
- domestic guinea pig(100716391) RAD51 homolog (S. cerevisiae)
- Domestic Rabbit(100008661) RAD51 homolog (S. cerevisiae)
- naked mole-rat(101715048) RAD51 homolog (S. cerevisiae)
- chicken(396086) RAD51 homolog (S. cerevisiae)
- Zebrafish(406487) RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
- Thale Cress(832208) DNA repair protein RAD51-like 1
- dog(403568) RAD51 homolog (S. cerevisiae)
- sheep(101109275) RAD51 homolog (S. cerevisiae)
- cow(514749) RAD51 homolog (S. cerevisiae)
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Antibodies
货号
说明
物种反应性
应用
抗-RAD51抗体, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-RAD51 Antibody, clone 1M8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, mouse, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-phospho-RAD51 (pTyr315) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
Anti-RAD51 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Proteins
货号
说明
物种
esiRNA
货号
说明
物种