跳转至内容
Merck
CN

PTPRK

protein tyrosine phosphatase, receptor type, K

别名:
R-PTP-kappa
物种:
UniProtKB ID:
基因ID:
  • Human(5796) Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq, Jul 2008]
  • Mouse(19272) protein tyrosine phosphatase, receptor type, K
  • Rat(360302) protein tyrosine phosphatase, receptor type, K
  • Zebrafish(555348) protein tyrosine phosphatase, receptor type, K
  • chicken(421711) protein tyrosine phosphatase, receptor type, K
  • Domestic Rabbit(100339990) protein tyrosine phosphatase, receptor type, K
  • domestic cat(101092366) protein tyrosine phosphatase, receptor type, K
  • dog(476290) protein tyrosine phosphatase, receptor type, K
  • Horse(100073063) protein tyrosine phosphatase, receptor type, K
  • cow(509657) protein tyrosine phosphatase, receptor type, K
  • sheep(101116916) protein tyrosine phosphatase, receptor type, K
  • domestic guinea pig(100730543) protein tyrosine phosphatase, receptor type, K
  • naked mole-rat(101723444) protein tyrosine phosphatase, receptor type, K

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-PTPRK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-PTPRK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-PTPRK antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
immunohistochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PTPRK,
物种
human