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Merck
CN

PPP2R1B

protein phosphatase 2, regulatory subunit A, beta

别名:
PP2A-Abeta, PR65B
物种:
UniProtKB ID:
基因ID:
  • Human(5519) Summary: This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
  • Mouse(73699) protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
  • Rat(315648) protein phosphatase 2, regulatory subunit A, beta
  • cow(282460) protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
  • dog(479444) protein phosphatase 2, regulatory subunit A, beta
  • cow(100138150) protein phosphatase 2, regulatory subunit A, beta
  • chicken(777130) protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
  • sheep(101108511) protein phosphatase 2, regulatory subunit A, beta
  • domestic guinea pig(100713478) protein phosphatase 2, regulatory subunit A, beta
  • Zebrafish(449548) protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
  • naked mole-rat(101722244) protein phosphatase 2, regulatory subunit A, beta
  • domestic cat(101081075) protein phosphatase 2, regulatory subunit A, beta

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Antibodies

货号
说明
物种反应性
应用
Anti-PPP2R1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Anti-PPP2R1B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-PPP2R1B antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

货号
说明
物种
斑蝥素, ,
物种
human

Kits

货号
说明
物种
Ser/Thr磷酸酶检测试剂盒1(K-R-pT-I-R-R), Ser/Thr Phosphatase Assay Kit 1used to detect PP2A activity by either dephosphorylation of the phosphopeptide.,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Ppp2r1b,
物种
mouse
MISSION® esiRNA, targeting human PPP2R1B,
物种
human