PLN
phospholamban
CMD1P, CMH18, PLB
Human PLN (5350), Mouse Pln (18821), Rat Pln (64672), chicken PLN (396378), dog PLN (414755), domestic cat PLN (101097897), cow PLN (100125240), sheep PLN (101102067), Domestic Rabbit PLN (100009299), domestic guinea pig Pln (100721387)
- Human(5350) Summary: The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008]
- Mouse(18821) phospholamban
- Rat(64672) phospholamban
- chicken(396378) phospholamban
- dog(414755) phospholamban
- domestic cat(101097897) phospholamban
- cow(100125240) phospholamban
- sheep(101102067) phospholamban
- Domestic Rabbit(100009299) phospholamban
- domestic guinea pig(100721387) phospholamban
- naked mole-rat(101699885) phospholamban
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Antibodies
抗磷酸化受磷酸蛋白(Ser16)抗体, Upstate®, from rabbit,
bovine, canine, human, mouse, pig, rabbit, rat
western blot
Anti-Phospholamban Antibody, clone 4J16 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
human, mouse, rat
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PLN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunohistochemistry
western blot
western blot
Anti-Phospho-PLN-T17 antibody produced in rabbit, ,
human, mouse, rat
immunohistochemistry
western blot
western blot
Anti-phospho-PLB (pSer16+Thr17) antibody produced in rabbit, affinity isolated antibody,
human, mouse, rat
ELISA
immunofluorescence
immunofluorescence