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Merck
CN

PIM1

pim-1 oncogene

别名:
PIM
物种:
UniProtKB ID:
基因ID:
  • Human(5292) Summary: The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011]
  • Mouse(18712) proviral integration site 1
  • Rat(24649) pim-1 oncogene
  • chicken(100858838) pim-1 oncogene
  • sheep(100272002) pim-1 oncogene
  • Horse(100053898) pim-1 oncogene
  • Zebrafish(58054) pim-1 oncogene
  • cow(281402) pim-1 oncogene
  • naked mole-rat(101706236) pim-1 oncogene
  • dog(481772) pim-1 oncogene
  • domestic guinea pig(100724588) pim-1 oncogene
  • domestic cat(493888) pim-1 oncogene

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-PIM1 antibody produced in mouse, clone 6A2, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry
Anti-PIM1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Anti-phospho-Pim-1 (pTyr309) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
ANTI-PIM1 antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Pim-1 (pTyr309) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot

Proteins

货号
说明
物种
PIM1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® 长非编码 esiRNA, targeting human PIM1,
物种
human
MISSION® esiRNA, targeting mouse Pim1,
物种
mouse