LEF1
lymphoid enhancer-binding factor 1
别名:
LEF-1, TCF10, TCF1ALPHA, TCF7L3
物种:
Human LEF1 (51176), Mouse Lef1 (16842), Rat Lef1 (161452), domestic guinea pig Lef1 (100716066), naked mole-rat Lef1 (101711023), dog LEF1 (478507), Zebrafish lef1 (30701), domestic cat LEF1 (101088077), cow LEF1 (535399), chicken LEF1 (395865)
UniProtKB ID:
基因ID:
- Human(51176) Summary: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
- Mouse(16842) lymphoid enhancer binding factor 1
- Rat(161452) lymphoid enhancer binding factor 1
- domestic guinea pig(100716066) lymphoid enhancer-binding factor 1
- naked mole-rat(101711023) lymphoid enhancer-binding factor 1
- dog(478507) lymphoid enhancer-binding factor 1
- Zebrafish(30701) lymphocyte enhancer binding factor 1
- domestic cat(101088077) lymphoid enhancer-binding factor 1
- cow(535399) lymphoid enhancer-binding factor 1
- chicken(395865) lymphoid enhancer-binding factor 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-LEF1 (AB1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, goat, human
应用
western blot
Anti-LEF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-LEF1 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Monoclonal Anti-LEF-1 (HMG DNA Binding Domain) antibody produced in mouse, ~1 mg/mL, clone REMB6, purified immunoglobulin,
物种反应性
human
应用
western blot
esiRNA
货号
说明
物种