KRIT1
KRIT1, ankyrin repeat containing
别名:
CAM, CCM1
物种:
Human KRIT1 (889), Mouse Krit1 (79264), Rat Krit1 (362317), Horse KRIT1 (100050998), Domestic Rabbit KRIT1 (100344408), cow KRIT1 (407996), domestic cat KRIT1 (101083757), naked mole-rat Krit1 (101725749), domestic guinea pig Krit1 (100731041), sheep KRIT1 (101110497) ...展开
UniProtKB ID:
基因ID:
- Human(889) Summary: This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
- Mouse(79264) KRIT1, ankyrin repeat containing
- Rat(362317) KRIT1, ankyrin repeat containing
- Horse(100050998) KRIT1, ankyrin repeat containing
- Domestic Rabbit(100344408) KRIT1, ankyrin repeat containing
- cow(407996) KRIT1, ankyrin repeat containing
- domestic cat(101083757) KRIT1, ankyrin repeat containing
- naked mole-rat(101725749) KRIT1, ankyrin repeat containing
- domestic guinea pig(100731041) KRIT1, ankyrin repeat containing
- sheep(101110497) KRIT1, ankyrin repeat containing
- chicken(420549) KRIT1, ankyrin repeat containing
- Zebrafish(321836) KRIT1, ankyrin repeat containing
- dog(482299) KRIT1, ankyrin repeat containing
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-KRIT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-KRIT1, (C-terminal) antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Monoclonal Anti-KRIT1 antibody produced in mouse, clone 2C7, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
Anti-KRIT-1 Antibody, clone 15, clone 15B2, from mouse,
物种反应性
human
应用
immunocytochemistry
immunoprecipitation (IP)
immunoprecipitation (IP)
Anti-KRIT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry